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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
H2AFX
All Species:
12.34
Human Site:
T137
Identified Species:
24.68
UniProt:
P16104
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16104
NP_002096.1
143
15145
T137
P
S
G
G
K
K
A
T
Q
A
S
Q
E
Y
_
Chimpanzee
Pan troglodytes
XP_520760
155
16635
D137
S
S
G
K
R
P
S
D
R
A
E
L
G
A
G
Rhesus Macaque
Macaca mulatta
XP_001090149
155
16475
D137
S
S
G
K
R
P
S
D
R
A
G
L
G
A
G
Dog
Lupus familis
XP_853256
242
25674
T236
P
A
G
G
K
K
A
T
Q
A
S
Q
E
Y
_
Cat
Felis silvestris
Mouse
Mus musculus
P27661
143
15124
S137
P
A
V
G
K
K
A
S
Q
A
S
Q
E
Y
_
Rat
Rattus norvegicus
P02262
130
14059
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512371
142
15010
Chicken
Gallus gallus
P02263
129
13922
Frog
Xenopus laevis
Q6GM86
139
14837
S133
S
T
S
G
K
K
S
S
Q
Q
S
Q
E
Y
_
Zebra Danio
Brachydanio rerio
Q7ZUY3
142
14983
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P84051
124
13344
K118
I
Q
A
V
L
L
P
K
K
T
E
K
K
A
_
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P16886
126
13432
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
79.3
58.6
N.A.
97.1
85.3
N.A.
93
85.3
84.6
87.4
N.A.
79
N.A.
N.A.
81.8
Protein Similarity:
100
81.2
81.9
59
N.A.
99.3
86.7
N.A.
94.4
86.7
90.2
90.2
N.A.
83.2
N.A.
N.A.
84.6
P-Site Identity:
100
20
20
92.8
N.A.
78.5
0
N.A.
0
0
57.1
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
46.6
46.6
100
N.A.
92.8
0
N.A.
0
0
78.5
0
N.A.
21.4
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
0
0
0
25
0
0
42
0
0
0
25
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
17
0
34
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
34
34
0
0
0
0
0
0
9
0
17
0
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
17
34
34
0
9
9
0
0
9
9
0
0
% K
% Leu:
0
0
0
0
9
9
0
0
0
0
0
17
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
25
0
0
0
0
17
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
34
9
0
34
0
0
0
% Q
% Arg:
0
0
0
0
17
0
0
0
17
0
0
0
0
0
0
% R
% Ser:
25
25
9
0
0
0
25
17
0
0
34
0
0
0
0
% S
% Thr:
0
9
0
0
0
0
0
17
0
9
0
0
0
0
0
% T
% Val:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
42
% _