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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACAN All Species: 6.36
Human Site: S958 Identified Species: 17.5
UniProt: P16112 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16112 NP_037359 2415 250193 S958 G D L S G L P S G E V L E T S
Chimpanzee Pan troglodytes Q5IS41 1321 142848 L155 D E Q D L V P L E V T G V V F
Rhesus Macaque Macaca mulatta XP_001091462 1544 155715 S340 G D L S G L P S G E V L E T S
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q61282 2132 221991 T960 T G R E G L E T S A S G V E D
Rat Rattus norvegicus P07897 2124 221100 T956 T G R G G L E T S A S G V E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521630 2020 206538 P854 A P E G S G L P S G V S G E H
Chicken Gallus gallus P07898 2109 223475 L943 P S G E E S G L A S G F P T I
Frog Xenopus laevis NP_001082106 1152 126842
Zebra Danio Brachydanio rerio XP_686182 1559 166402 A393 H P D S R Y D A F C Y S E T G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.5 55.1 N.A. N.A. 69.1 68.7 N.A. 49.1 47.1 24.1 36.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 35.4 58.2 N.A. N.A. 75.4 74.6 N.A. 58.5 59.4 34.9 45.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 N.A. N.A. 13.3 13.3 N.A. 6.6 6.6 0 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 100 N.A. N.A. 20 20 N.A. 6.6 6.6 0 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 0 0 0 12 12 23 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % C
% Asp: 12 23 12 12 0 0 12 0 0 0 0 0 0 0 23 % D
% Glu: 0 12 12 23 12 0 23 0 12 23 0 0 34 34 0 % E
% Phe: 0 0 0 0 0 0 0 0 12 0 0 12 0 0 12 % F
% Gly: 23 23 12 23 45 12 12 0 23 12 12 34 12 0 12 % G
% His: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 23 0 12 45 12 23 0 0 0 23 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 12 23 0 0 0 0 34 12 0 0 0 0 12 0 0 % P
% Gln: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 23 0 12 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 12 0 34 12 12 0 23 34 12 23 23 0 0 23 % S
% Thr: 23 0 0 0 0 0 0 23 0 0 12 0 0 45 0 % T
% Val: 0 0 0 0 0 12 0 0 0 12 34 0 34 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 12 0 0 0 0 12 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _