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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITGB4 All Species: 9.09
Human Site: S1518 Identified Species: 40
UniProt: P16144 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16144 NP_000204.3 1822 202151 S1518 S T L T S V S S H D S R L T A
Chimpanzee Pan troglodytes XP_001138138 1963 216944 S1659 S T L T S V S S H D F R L T A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_540437 1865 206300 T1552 V S H R V L S T S S T L T R D
Cat Felis silvestris
Mouse Mus musculus A2A863 1818 201632 S1514 S T L T S L S S Q D S R G A V
Rat Rattus norvegicus Q64632 1807 200571 G1502 Q S A A P S W G T D S R G A M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001019557 1893 210706 N1589 L S G G L L D N L E S R F T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.4 N.A. 80.6 N.A. 88.2 82.2 N.A. N.A. N.A. N.A. 51.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 88.8 N.A. 85.6 N.A. 93 88.3 N.A. N.A. N.A. N.A. 66.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 N.A. 6.6 N.A. 66.6 20 N.A. N.A. N.A. N.A. 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 N.A. 33.3 N.A. 73.3 26.6 N.A. N.A. N.A. N.A. 46.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 17 0 0 0 0 0 0 0 0 0 34 34 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 17 0 0 67 0 0 0 0 17 % D
% Glu: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 17 0 17 0 0 % F
% Gly: 0 0 17 17 0 0 0 17 0 0 0 0 34 0 0 % G
% His: 0 0 17 0 0 0 0 0 34 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 17 0 50 0 17 50 0 0 17 0 0 17 34 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % M
% Asn: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 17 % P
% Gln: 17 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % Q
% Arg: 0 0 0 17 0 0 0 0 0 0 0 84 0 17 0 % R
% Ser: 50 50 0 0 50 17 67 50 17 17 67 0 0 0 0 % S
% Thr: 0 50 0 50 0 0 0 17 17 0 17 0 17 50 0 % T
% Val: 17 0 0 0 17 34 0 0 0 0 0 0 0 0 17 % V
% Trp: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _