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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACADS
All Species:
13.03
Human Site:
S176
Identified Species:
22.05
UniProt:
P16219
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16219
NP_000008.1
412
44297
S176
T
A
R
A
E
G
D
S
W
V
L
N
G
T
K
Chimpanzee
Pan troglodytes
A5A6I0
421
46589
I185
K
K
G
D
E
Y
I
I
N
G
Q
K
M
W
I
Rhesus Macaque
Macaca mulatta
XP_001091115
412
44327
S176
T
A
R
A
E
G
D
S
W
V
L
N
G
T
K
Dog
Lupus familis
XP_534712
404
43890
A168
T
A
Q
A
D
G
D
A
W
I
L
N
G
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q07417
412
44928
S176
T
A
R
E
E
G
D
S
W
V
L
N
G
T
K
Rat
Rattus norvegicus
P15651
412
44747
S176
T
A
R
E
E
G
D
S
W
V
L
N
G
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519538
350
37289
A127
T
K
A
W
I
T
N
A
W
D
A
S
A
T
V
Chicken
Gallus gallus
NP_001006193
416
44596
E180
V
A
R
L
D
G
D
E
W
V
L
N
G
T
K
Frog
Xenopus laevis
NP_001080869
409
44373
E173
T
A
K
L
D
G
E
E
W
V
L
N
G
T
K
Zebra Danio
Brachydanio rerio
NP_001003743
405
43530
E169
L
A
Q
Q
E
G
N
E
W
V
L
N
G
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSA3
419
45853
I181
K
K
G
D
E
W
V
I
N
G
Q
K
M
W
I
Honey Bee
Apis mellifera
XP_623170
408
44590
N171
I
A
K
L
N
G
S
N
Y
L
I
N
G
T
K
Nematode Worm
Caenorhab. elegans
Q22347
417
44800
I175
K
K
G
D
E
Y
I
I
N
G
S
K
A
W
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SWG0
409
44755
G175
K
A
E
K
V
D
G
G
Y
I
L
N
G
N
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.5
99
89
N.A.
89.8
90.2
N.A.
76.4
82.4
79.3
73.7
N.A.
37.7
64.8
37.8
N.A.
Protein Similarity:
100
56
99
92.4
N.A.
93.9
94.4
N.A.
80.5
90.6
89
86.6
N.A.
56
81.5
57
N.A.
P-Site Identity:
100
6.6
100
73.3
N.A.
93.3
93.3
N.A.
20
73.3
66.6
66.6
N.A.
6.6
40
6.6
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
40
80
86.6
80
N.A.
6.6
73.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
72
8
22
0
0
0
15
0
0
8
0
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
22
22
8
43
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
8
15
58
0
8
22
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
22
0
0
65
8
8
0
22
0
0
72
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
15
22
0
15
8
0
0
0
22
% I
% Lys:
29
29
15
8
0
0
0
0
0
0
0
22
0
0
72
% K
% Leu:
8
0
0
22
0
0
0
0
0
8
65
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% M
% Asn:
0
0
0
0
8
0
15
8
22
0
0
72
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
15
8
0
0
0
0
0
0
15
0
0
0
0
% Q
% Arg:
0
0
36
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
29
0
0
8
8
0
0
0
% S
% Thr:
50
0
0
0
0
8
0
0
0
0
0
0
0
72
0
% T
% Val:
8
0
0
0
8
0
8
0
0
50
0
0
0
0
8
% V
% Trp:
0
0
0
8
0
8
0
0
65
0
0
0
0
22
0
% W
% Tyr:
0
0
0
0
0
15
0
0
15
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _