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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACADS
All Species:
9.09
Human Site:
S252
Identified Species:
15.38
UniProt:
P16219
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16219
NP_000008.1
412
44297
S252
D
C
R
I
P
K
D
S
I
L
G
E
P
G
M
Chimpanzee
Pan troglodytes
A5A6I0
421
46589
N261
D
V
K
V
P
R
E
N
V
L
I
G
D
G
A
Rhesus Macaque
Macaca mulatta
XP_001091115
412
44327
S252
D
C
R
I
P
K
D
S
I
L
G
E
P
G
M
Dog
Lupus familis
XP_534712
404
43890
S244
D
C
R
I
P
K
D
S
L
L
G
E
P
G
M
Cat
Felis silvestris
Mouse
Mus musculus
Q07417
412
44928
N252
D
C
R
I
P
K
E
N
L
L
G
E
P
G
M
Rat
Rattus norvegicus
P15651
412
44747
N252
D
C
R
I
P
K
E
N
L
L
G
E
P
G
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519538
350
37289
M203
G
Q
G
F
K
I
A
M
Q
T
L
D
M
G
R
Chicken
Gallus gallus
NP_001006193
416
44596
N256
D
C
R
I
P
K
A
N
L
L
G
Q
L
G
M
Frog
Xenopus laevis
NP_001080869
409
44373
N249
D
C
R
I
P
R
K
N
L
L
G
Q
P
G
M
Zebra Danio
Brachydanio rerio
NP_001003743
405
43530
N245
D
C
R
I
P
L
G
N
M
L
G
E
R
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSA3
419
45853
N257
D
V
R
V
P
K
E
N
V
L
I
G
E
G
A
Honey Bee
Apis mellifera
XP_623170
408
44590
N247
D
C
K
L
P
K
E
N
L
L
G
E
S
G
M
Nematode Worm
Caenorhab. elegans
Q22347
417
44800
N251
D
V
R
V
P
A
E
N
V
L
G
A
P
G
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SWG0
409
44755
N251
N
C
F
V
P
E
E
N
I
L
D
K
E
G
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.5
99
89
N.A.
89.8
90.2
N.A.
76.4
82.4
79.3
73.7
N.A.
37.7
64.8
37.8
N.A.
Protein Similarity:
100
56
99
92.4
N.A.
93.9
94.4
N.A.
80.5
90.6
89
86.6
N.A.
56
81.5
57
N.A.
P-Site Identity:
100
26.6
100
93.3
N.A.
80
80
N.A.
6.6
66.6
66.6
66.6
N.A.
40
60
46.6
N.A.
P-Site Similarity:
100
66.6
100
100
N.A.
100
100
N.A.
13.3
86.6
93.3
80
N.A.
66.6
93.3
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
15
0
0
0
0
8
0
0
22
% A
% Cys:
0
72
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
86
0
0
0
0
0
22
0
0
0
8
8
8
0
0
% D
% Glu:
0
0
0
0
0
8
50
0
0
0
0
50
15
0
0
% E
% Phe:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
0
0
8
0
0
0
72
15
0
100
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
58
0
8
0
0
22
0
15
0
0
0
0
% I
% Lys:
0
0
15
0
8
58
8
0
0
0
0
8
0
0
8
% K
% Leu:
0
0
0
8
0
8
0
0
43
93
8
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
8
8
0
0
0
8
0
65
% M
% Asn:
8
0
0
0
0
0
0
72
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
93
0
0
0
0
0
0
0
50
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
8
0
0
15
0
0
0
% Q
% Arg:
0
0
72
0
0
15
0
0
0
0
0
0
8
0
8
% R
% Ser:
0
0
0
0
0
0
0
22
0
0
0
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% T
% Val:
0
22
0
29
0
0
0
0
22
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _