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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACADS
All Species:
33.94
Human Site:
T141
Identified Species:
57.44
UniProt:
P16219
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16219
NP_000008.1
412
44297
T141
E
Q
K
Q
A
W
V
T
P
F
T
S
G
D
K
Chimpanzee
Pan troglodytes
A5A6I0
421
46589
T150
K
K
Y
L
G
R
M
T
E
E
P
L
M
C
A
Rhesus Macaque
Macaca mulatta
XP_001091115
412
44327
T141
E
Q
K
Q
K
W
V
T
P
F
T
S
G
D
K
Dog
Lupus familis
XP_534712
404
43890
T133
E
Q
K
Q
Q
W
I
T
P
F
T
S
G
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q07417
412
44928
T141
Q
Q
K
Q
Q
W
I
T
P
F
T
N
G
D
K
Rat
Rattus norvegicus
P15651
412
44747
T141
Q
Q
K
Q
Q
W
I
T
P
F
T
N
G
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519538
350
37289
L92
D
K
I
G
C
F
A
L
S
E
P
G
N
G
S
Chicken
Gallus gallus
NP_001006193
416
44596
S145
E
Q
K
H
K
W
I
S
P
F
T
S
G
D
K
Frog
Xenopus laevis
NP_001080869
409
44373
S138
E
Q
K
R
Q
W
I
S
P
F
C
S
G
D
K
Zebra Danio
Brachydanio rerio
NP_001003743
405
43530
T134
E
Q
K
K
Q
W
I
T
P
F
T
T
G
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSA3
419
45853
L146
K
K
Y
L
G
R
L
L
E
E
P
L
V
A
A
Honey Bee
Apis mellifera
XP_623170
408
44590
T136
D
Q
I
K
K
Y
I
T
P
F
T
T
G
T
K
Nematode Worm
Caenorhab. elegans
Q22347
417
44800
A140
K
K
Y
L
G
A
L
A
A
E
P
I
I
A
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SWG0
409
44755
P140
A
Q
K
E
K
Y
L
P
K
L
I
S
G
E
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.5
99
89
N.A.
89.8
90.2
N.A.
76.4
82.4
79.3
73.7
N.A.
37.7
64.8
37.8
N.A.
Protein Similarity:
100
56
99
92.4
N.A.
93.9
94.4
N.A.
80.5
90.6
89
86.6
N.A.
56
81.5
57
N.A.
P-Site Identity:
100
6.6
93.3
86.6
N.A.
73.3
73.3
N.A.
0
73.3
66.6
66.6
N.A.
0
46.6
0
N.A.
P-Site Similarity:
100
26.6
93.3
93.3
N.A.
93.3
93.3
N.A.
20
86.6
86.6
93.3
N.A.
20
80
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
8
8
8
8
0
0
0
0
15
15
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
8
0
0
8
0
% C
% Asp:
15
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% D
% Glu:
43
0
0
8
0
0
0
0
15
29
0
0
0
15
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
65
0
0
0
0
0
% F
% Gly:
0
0
0
8
22
0
0
0
0
0
0
8
72
8
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
15
0
0
0
50
0
0
0
8
8
8
0
0
% I
% Lys:
22
29
65
15
29
0
0
0
8
0
0
0
0
0
65
% K
% Leu:
0
0
0
22
0
0
22
15
0
8
0
15
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
15
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
65
0
29
0
0
0
0
% P
% Gln:
15
72
0
36
36
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
15
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
15
8
0
0
43
0
0
15
% S
% Thr:
0
0
0
0
0
0
0
58
0
0
58
15
0
8
0
% T
% Val:
0
0
0
0
0
0
15
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
58
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
22
0
0
15
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _