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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACADS
All Species:
38.18
Human Site:
T223
Identified Species:
64.62
UniProt:
P16219
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16219
NP_000008.1
412
44297
T223
P
M
P
T
P
G
L
T
L
G
K
K
E
D
K
Chimpanzee
Pan troglodytes
A5A6I0
421
46589
Q232
E
A
D
T
P
G
I
Q
I
G
R
K
E
L
N
Rhesus Macaque
Macaca mulatta
XP_001091115
412
44327
T223
P
M
P
T
P
G
L
T
L
G
K
K
E
D
K
Dog
Lupus familis
XP_534712
404
43890
T215
P
M
P
T
S
G
L
T
L
G
K
K
E
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q07417
412
44928
T223
P
M
P
T
P
G
L
T
L
G
K
K
E
D
K
Rat
Rattus norvegicus
P15651
412
44747
T223
P
M
P
T
P
G
L
T
L
G
K
K
E
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519538
350
37289
S174
D
K
L
G
I
R
A
S
S
T
A
N
L
I
F
Chicken
Gallus gallus
NP_001006193
416
44596
S227
P
M
P
T
A
G
L
S
L
G
K
K
E
D
K
Frog
Xenopus laevis
NP_001080869
409
44373
S220
E
M
P
T
P
G
L
S
L
G
K
K
E
D
K
Zebra Danio
Brachydanio rerio
NP_001003743
405
43530
S216
P
M
P
H
P
G
L
S
L
G
K
K
E
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSA3
419
45853
T228
E
R
D
S
P
G
L
T
P
G
R
K
E
L
N
Honey Bee
Apis mellifera
XP_623170
408
44590
F218
D
K
T
T
E
G
L
F
V
G
K
K
E
D
K
Nematode Worm
Caenorhab. elegans
Q22347
417
44800
T222
D
G
D
T
P
G
I
T
R
G
K
K
E
K
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SWG0
409
44755
S222
E
K
G
M
T
G
F
S
T
A
Q
K
L
D
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.5
99
89
N.A.
89.8
90.2
N.A.
76.4
82.4
79.3
73.7
N.A.
37.7
64.8
37.8
N.A.
Protein Similarity:
100
56
99
92.4
N.A.
93.9
94.4
N.A.
80.5
90.6
89
86.6
N.A.
56
81.5
57
N.A.
P-Site Identity:
100
40
100
93.3
N.A.
100
100
N.A.
0
86.6
86.6
86.6
N.A.
46.6
60
53.3
N.A.
P-Site Similarity:
100
60
100
93.3
N.A.
100
100
N.A.
6.6
93.3
93.3
93.3
N.A.
60
66.6
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
8
0
0
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
22
0
22
0
0
0
0
0
0
0
0
0
0
72
0
% D
% Glu:
29
0
0
0
8
0
0
0
0
0
0
0
86
0
0
% E
% Phe:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
8
% F
% Gly:
0
8
8
8
0
93
0
0
0
86
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
15
0
8
0
0
0
0
8
0
% I
% Lys:
0
22
0
0
0
0
0
0
0
0
72
93
0
8
72
% K
% Leu:
0
0
8
0
0
0
72
0
58
0
0
0
15
15
0
% L
% Met:
0
58
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
22
% N
% Pro:
50
0
58
0
65
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% Q
% Arg:
0
8
0
0
0
8
0
0
8
0
15
0
0
0
0
% R
% Ser:
0
0
0
8
8
0
0
36
8
0
0
0
0
0
0
% S
% Thr:
0
0
8
72
8
0
0
50
8
8
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _