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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDGFRA
All Species:
30.61
Human Site:
Y685
Identified Species:
67.33
UniProt:
P16234
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16234
NP_006197.1
1089
122670
Y685
F
Y
G
D
L
V
N
Y
L
H
K
N
R
D
S
Chimpanzee
Pan troglodytes
XP_518034
1082
120774
Y668
R
Y
G
D
L
V
D
Y
L
H
R
N
K
H
T
Rhesus Macaque
Macaca mulatta
XP_001107595
1106
124189
Y692
R
Y
G
D
L
V
D
Y
L
H
R
N
K
H
T
Dog
Lupus familis
XP_532374
1089
122830
Y685
F
Y
G
D
L
V
N
Y
L
H
K
N
R
D
S
Cat
Felis silvestris
Mouse
Mus musculus
P26618
1089
122665
Y685
F
Y
G
D
L
V
N
Y
L
H
K
N
R
D
S
Rat
Rattus norvegicus
P20786
1088
122624
Y684
F
Y
G
D
L
V
N
Y
L
H
K
N
R
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514918
1045
115090
G667
I
A
V
E
A
H
V
G
D
R
D
T
M
E
S
Chicken
Gallus gallus
Q9PUF6
1087
122922
Y685
F
Y
G
D
L
V
N
Y
L
H
K
N
R
D
N
Frog
Xenopus laevis
P26619
1087
122680
Y687
F
Y
G
D
L
V
N
Y
L
H
K
N
R
D
N
Zebra Danio
Brachydanio rerio
Q9DE49
1059
118193
K663
D
L
V
N
Y
L
H
K
N
R
D
G
F
L
S
Tiger Blowfish
Takifugu rubipres
Q8AXC7
1062
118619
K664
D
L
V
N
Y
L
H
K
N
R
E
S
F
L
N
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45
44.2
95.6
N.A.
91.8
90.9
N.A.
62.8
80.3
75.5
60.8
61.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
63.2
63.5
97.9
N.A.
96.2
95.9
N.A.
70.1
89.1
85.1
75.4
75.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
60
60
100
N.A.
100
100
N.A.
6.6
93.3
93.3
6.6
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
86.6
100
N.A.
100
100
N.A.
20
100
100
26.6
40
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
0
73
0
0
19
0
10
0
19
0
0
55
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
10
0
0
10
0
% E
% Phe:
55
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% F
% Gly:
0
0
73
0
0
0
0
10
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
10
19
0
0
73
0
0
0
19
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
19
0
0
55
0
19
0
0
% K
% Leu:
0
19
0
0
73
19
0
0
73
0
0
0
0
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
19
0
0
55
0
19
0
0
73
0
0
28
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
19
0
0
0
0
0
0
0
0
28
19
0
55
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
55
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
19
% T
% Val:
0
0
28
0
0
73
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
73
0
0
19
0
0
73
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _