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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDGFRA All Species: 33.03
Human Site: Y754 Identified Species: 72.67
UniProt: P16234 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16234 NP_006197.1 1089 122670 Y754 E R K E V S K Y S D I Q R S L
Chimpanzee Pan troglodytes XP_518034 1082 120774 Y739 D M K G D V K Y A D I E S S N
Rhesus Macaque Macaca mulatta XP_001107595 1106 124189 Y763 D M K G D V K Y A D I E S S N
Dog Lupus familis XP_532374 1089 122830 Y754 E R K E V S K Y S D I Q R S L
Cat Felis silvestris
Mouse Mus musculus P26618 1089 122665 Y754 E R K E V S K Y S D I Q R S L
Rat Rattus norvegicus P20786 1088 122624 Y753 E R K E V S K Y S D I Q R S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514918 1045 115090 V731 V L L V I V I V S L I V L V I
Chicken Gallus gallus Q9PUF6 1087 122922 Y754 E R K E G S K Y S D I Q R S V
Frog Xenopus laevis P26619 1087 122680 Y756 E M K E P S K Y S D I Q R S L
Zebra Danio Brachydanio rerio Q9DE49 1059 118193 Y729 E M N E A S K Y S P I Q R S D
Tiger Blowfish Takifugu rubipres Q8AXC7 1062 118619 Y731 E I S N A S K Y S D L Q G S N
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45 44.2 95.6 N.A. 91.8 90.9 N.A. 62.8 80.3 75.5 60.8 61.6 N.A. N.A. N.A. N.A.
Protein Similarity: 100 63.2 63.5 97.9 N.A. 96.2 95.9 N.A. 70.1 89.1 85.1 75.4 75.3 N.A. N.A. N.A. N.A.
P-Site Identity: 100 40 40 100 N.A. 100 100 N.A. 13.3 86.6 86.6 66.6 53.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 60 60 100 N.A. 100 100 N.A. 26.6 93.3 86.6 66.6 60 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 19 0 0 0 19 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 19 0 0 0 19 0 0 0 0 82 0 0 0 0 10 % D
% Glu: 73 0 0 64 0 0 0 0 0 0 0 19 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 19 10 0 0 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 10 0 10 0 0 0 91 0 0 0 10 % I
% Lys: 0 0 73 0 0 0 91 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 10 0 0 0 0 0 0 10 10 0 10 0 46 % L
% Met: 0 37 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 28 % N
% Pro: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 73 0 0 0 % Q
% Arg: 0 46 0 0 0 0 0 0 0 0 0 0 64 0 0 % R
% Ser: 0 0 10 0 0 73 0 0 82 0 0 0 19 91 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 10 0 0 10 37 28 0 10 0 0 0 10 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 91 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _