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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A16 All Species: 19.39
Human Site: S230 Identified Species: 28.44
UniProt: P16260 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16260 NP_689920.1 332 36224 S230 T L L G R P S S D N P N V L V
Chimpanzee Pan troglodytes XP_001168284 332 36249 S230 T L L G R P S S D N P N V L V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_546134 332 36141 S230 T L L G R P S S D N P N V L V
Cat Felis silvestris
Mouse Mus musculus Q8C0K5 332 36201 S230 A L L G R P S S D N P N V L V
Rat Rattus norvegicus P16261 322 35038 A224 K S V G L S Y A P T L L G R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520566 324 35638 S222 T L L G R P S S D N P N V L V
Chicken Gallus gallus XP_421570 320 35184 L218 N L L G R P S L D N P D V L V
Frog Xenopus laevis Q5PQ27 327 36043 Y228 H S G R T Q P Y T F E R L L F
Zebra Danio Brachydanio rerio Q0P483 321 35318 H217 Y E T L K K T H A E K T G R A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624199 316 35726 L216 R N T G G L V L T I P A R L L
Nematode Worm Caenorhab. elegans Q20799 588 66319 V442 T N S S E P G V L A L L A C G
Sea Urchin Strong. purpuratus XP_789697 271 30376 T173 T A K I F L L T K G P P Q F S
Poplar Tree Populus trichocarpa XP_002308549 340 37252 C241 S I V M R L S C G A I A G L F
Maize Zea mays P29518 436 46609 G325 R R P G A D V G P V A T L L I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172908 331 36237 P232 N S V R M H L P C G A L A G L
Baker's Yeast Sacchar. cerevisiae P38702 357 40807 L245 A P Y S V L E L S E D D E L E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 96 N.A. 92.7 88.8 N.A. 82.5 81 37 38.2 N.A. N.A. 50.2 20.2 39.7
Protein Similarity: 100 99.6 N.A. 98.1 N.A. 96.6 92.7 N.A. 87.9 86.7 54.2 53.9 N.A. N.A. 62 31.6 53.6
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 6.6 N.A. 100 80 6.6 0 N.A. N.A. 20 13.3 13.3
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 20 N.A. 100 86.6 13.3 13.3 N.A. N.A. 26.6 13.3 20
Percent
Protein Identity: 34.4 21.7 N.A. 37.9 37.5 N.A.
Protein Similarity: 54.4 34.8 N.A. 53.6 55.1 N.A.
P-Site Identity: 20 13.3 N.A. 0 6.6 N.A.
P-Site Similarity: 40 26.6 N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 7 0 0 7 0 0 7 7 13 13 13 13 0 7 % A
% Cys: 0 0 0 0 0 0 0 7 7 0 0 0 0 7 0 % C
% Asp: 0 0 0 0 0 7 0 0 38 0 7 13 0 0 0 % D
% Glu: 0 7 0 0 7 0 7 0 0 13 7 0 7 0 7 % E
% Phe: 0 0 0 0 7 0 0 0 0 7 0 0 0 7 13 % F
% Gly: 0 0 7 57 7 0 7 7 7 13 0 0 19 7 7 % G
% His: 7 0 0 0 0 7 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 7 0 0 0 0 0 7 7 0 0 0 7 % I
% Lys: 7 0 7 0 7 7 0 0 7 0 7 0 0 0 0 % K
% Leu: 0 38 38 7 7 25 13 19 7 0 13 19 13 69 13 % L
% Met: 0 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 13 13 0 0 0 0 0 0 0 38 0 32 0 0 0 % N
% Pro: 0 7 7 0 0 44 7 7 13 0 50 7 0 0 7 % P
% Gln: 0 0 0 0 0 7 0 0 0 0 0 0 7 0 0 % Q
% Arg: 13 7 0 13 44 0 0 0 0 0 0 7 7 13 0 % R
% Ser: 7 19 7 13 0 7 44 32 7 0 0 0 0 0 7 % S
% Thr: 38 0 13 0 7 0 7 7 13 7 0 13 0 0 0 % T
% Val: 0 0 19 0 7 0 13 7 0 7 0 0 38 0 38 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 7 0 0 0 7 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _