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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A16 All Species: 24.24
Human Site: T240 Identified Species: 35.56
UniProt: P16260 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16260 NP_689920.1 332 36224 T240 P N V L V L K T H V N L L C G
Chimpanzee Pan troglodytes XP_001168284 332 36249 T240 P N V L V L K T H V N L L C G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_546134 332 36141 T240 P N V L V L K T H I N L L C G
Cat Felis silvestris
Mouse Mus musculus Q8C0K5 332 36201 T240 P N V L V L K T H I N L L C G
Rat Rattus norvegicus P16261 322 35038 D234 L L G R P S S D N P N V L V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520566 324 35638 T232 P N V L V L K T H I N L L C G
Chicken Gallus gallus XP_421570 320 35184 T228 P D V L V L K T H I N L L C G
Frog Xenopus laevis Q5PQ27 327 36043 C238 E R L L F G A C A G L F G Q S
Zebra Danio Brachydanio rerio Q0P483 321 35318 F227 K T G R A H P F P Y E R L V F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624199 316 35726 G226 P A R L L C G G I A G A V A Q
Nematode Worm Caenorhab. elegans Q20799 588 66319 S452 L L A C G T C S S T C G Q L S
Sea Urchin Strong. purpuratus XP_789697 271 30376 I183 P P Q F S K P I P N N P S E R
Poplar Tree Populus trichocarpa XP_002308549 340 37252 T251 I A G L F G Q T I T Y P L D V
Maize Zea mays P29518 436 46609 A335 A T L L I G S A A G A I A S S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172908 331 36237 Q242 A L A G L F G Q T I T Y P L D
Baker's Yeast Sacchar. cerevisiae P38702 357 40807 Q255 D D E L E R V Q K K Q R R P L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 96 N.A. 92.7 88.8 N.A. 82.5 81 37 38.2 N.A. N.A. 50.2 20.2 39.7
Protein Similarity: 100 99.6 N.A. 98.1 N.A. 96.6 92.7 N.A. 87.9 86.7 54.2 53.9 N.A. N.A. 62 31.6 53.6
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 13.3 N.A. 93.3 86.6 6.6 6.6 N.A. N.A. 13.3 0 13.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 26.6 N.A. 100 100 13.3 6.6 N.A. N.A. 26.6 6.6 13.3
Percent
Protein Identity: 34.4 21.7 N.A. 37.9 37.5 N.A.
Protein Similarity: 54.4 34.8 N.A. 53.6 55.1 N.A.
P-Site Identity: 20 6.6 N.A. 0 6.6 N.A.
P-Site Similarity: 26.6 26.6 N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 13 13 0 7 0 7 7 13 7 7 7 7 7 0 % A
% Cys: 0 0 0 7 0 7 7 7 0 0 7 0 0 38 0 % C
% Asp: 7 13 0 0 0 0 0 7 0 0 0 0 0 7 7 % D
% Glu: 7 0 7 0 7 0 0 0 0 0 7 0 0 7 0 % E
% Phe: 0 0 0 7 13 7 0 7 0 0 0 7 0 0 7 % F
% Gly: 0 0 19 7 7 19 13 7 0 13 7 7 7 0 38 % G
% His: 0 0 0 0 0 7 0 0 38 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 7 0 0 7 13 32 0 7 0 0 0 % I
% Lys: 7 0 0 0 0 7 38 0 7 7 0 0 0 0 0 % K
% Leu: 13 19 13 69 13 38 0 0 0 0 7 38 57 13 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 32 0 0 0 0 0 0 7 7 50 0 0 0 0 % N
% Pro: 50 7 0 0 7 0 13 0 13 7 0 13 7 7 0 % P
% Gln: 0 0 7 0 0 0 7 13 0 0 7 0 7 7 7 % Q
% Arg: 0 7 7 13 0 7 0 0 0 0 0 13 7 0 7 % R
% Ser: 0 0 0 0 7 7 13 7 7 0 0 0 7 7 19 % S
% Thr: 0 13 0 0 0 7 0 44 7 13 7 0 0 0 0 % T
% Val: 0 0 38 0 38 0 7 0 0 13 0 7 7 13 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 7 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _