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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A16 All Species: 18.48
Human Site: T272 Identified Species: 27.11
UniProt: P16260 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16260 NP_689920.1 332 36224 T272 R R R M Q L G T V L P E F E K
Chimpanzee Pan troglodytes XP_001168284 332 36249 T272 R R R M Q L G T V L P E F E K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_546134 332 36141 T272 R R R M Q L G T A L P E F E K
Cat Felis silvestris
Mouse Mus musculus Q8C0K5 332 36201 A272 R R R M Q L G A V L P E F E K
Rat Rattus norvegicus P16261 322 35038 D265 Q T I S Y P F D V T R R R M Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520566 324 35638 T264 R R R M Q L G T V L P D S E K
Chicken Gallus gallus XP_421570 320 35184 A260 R R R M Q L G A V L P D S E K
Frog Xenopus laevis Q5PQ27 327 36043 S269 V T G H T Y G S I I G T M Q E
Zebra Danio Brachydanio rerio Q0P483 321 35318 T258 V V R R R M Q T A G V T G H T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624199 316 35726 Y258 M H H A N H K Y S S S M L Q T
Nematode Worm Caenorhab. elegans Q20799 588 66319 T484 R Y S P Q P D T M F G Q F K Y
Sea Urchin Strong. purpuratus XP_789697 271 30376 I214 I A Q T I T H I M Q N L K T V
Poplar Tree Populus trichocarpa XP_002308549 340 37252 F282 N A R Y R N T F E G L S T I V
Maize Zea mays P29518 436 46609 Q366 V G G R Q V Y Q N V L H A I Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172908 331 36237 N274 G N N K R Y K N T F D G L N T
Baker's Yeast Sacchar. cerevisiae P38702 357 40807 A296 R R R L Q V S A L S P K T M Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 96 N.A. 92.7 88.8 N.A. 82.5 81 37 38.2 N.A. N.A. 50.2 20.2 39.7
Protein Similarity: 100 99.6 N.A. 98.1 N.A. 96.6 92.7 N.A. 87.9 86.7 54.2 53.9 N.A. N.A. 62 31.6 53.6
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 6.6 N.A. 86.6 80 6.6 13.3 N.A. N.A. 0 26.6 0
P-Site Similarity: 100 100 N.A. 93.3 N.A. 93.3 20 N.A. 93.3 86.6 40 26.6 N.A. N.A. 6.6 46.6 13.3
Percent
Protein Identity: 34.4 21.7 N.A. 37.9 37.5 N.A.
Protein Similarity: 54.4 34.8 N.A. 53.6 55.1 N.A.
P-Site Identity: 6.6 6.6 N.A. 0 33.3 N.A.
P-Site Similarity: 13.3 20 N.A. 6.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 7 0 0 0 19 13 0 0 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 7 7 0 0 7 13 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 7 0 0 25 0 38 7 % E
% Phe: 0 0 0 0 0 0 7 7 0 13 0 0 32 0 0 % F
% Gly: 7 7 13 0 0 0 44 0 0 13 13 7 7 0 0 % G
% His: 0 7 7 7 0 7 7 0 0 0 0 7 0 7 0 % H
% Ile: 7 0 7 0 7 0 0 7 7 7 0 0 0 13 0 % I
% Lys: 0 0 0 7 0 0 13 0 0 0 0 7 7 7 38 % K
% Leu: 0 0 0 7 0 38 0 0 7 38 13 7 13 0 0 % L
% Met: 7 0 0 38 0 7 0 0 13 0 0 7 7 13 0 % M
% Asn: 7 7 7 0 7 7 0 7 7 0 7 0 0 7 0 % N
% Pro: 0 0 0 7 0 13 0 0 0 0 44 0 0 0 0 % P
% Gln: 7 0 7 0 57 0 7 7 0 7 0 7 0 13 7 % Q
% Arg: 50 44 57 13 19 0 0 0 0 0 7 7 7 0 0 % R
% Ser: 0 0 7 7 0 0 7 7 7 13 7 7 13 0 0 % S
% Thr: 0 13 0 7 7 7 7 38 7 7 0 13 13 7 19 % T
% Val: 19 7 0 0 0 13 0 0 38 7 7 0 0 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 7 7 13 7 7 0 0 0 0 0 0 19 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _