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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A16
All Species:
36.06
Human Site:
Y189
Identified Species:
52.89
UniProt:
P16260
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16260
NP_689920.1
332
36224
Y189
E
G
G
F
F
G
F
Y
R
G
L
M
P
T
I
Chimpanzee
Pan troglodytes
XP_001168284
332
36249
Y189
E
G
G
F
F
G
F
Y
R
G
L
M
P
T
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546134
332
36141
Y189
E
G
G
F
L
G
F
Y
R
G
L
M
P
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0K5
332
36201
Y189
E
G
G
F
L
G
F
Y
R
G
L
M
P
T
I
Rat
Rattus norvegicus
P16261
322
35038
A183
H
A
F
K
T
I
Y
A
K
E
G
G
F
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520566
324
35638
Y181
E
G
G
F
R
G
F
Y
R
G
L
M
P
T
I
Chicken
Gallus gallus
XP_421570
320
35184
Y177
E
G
G
F
S
G
F
Y
R
G
L
M
P
T
I
Frog
Xenopus laevis
Q5PQ27
327
36043
K187
M
S
R
E
E
G
L
K
S
L
Y
R
G
F
T
Zebra Danio
Brachydanio rerio
Q0P483
321
35318
F176
Y
S
N
I
M
D
V
F
V
R
I
S
R
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624199
316
35726
F175
R
G
F
W
P
T
I
F
G
M
I
P
Y
A
G
Nematode Worm
Caenorhab. elegans
Q20799
588
66319
Y401
K
E
G
I
R
C
F
Y
K
G
Y
L
P
N
L
Sea Urchin
Strong. purpuratus
XP_789697
271
30376
I132
I
I
H
T
F
Y
T
I
W
H
H
E
G
Q
F
Poplar Tree
Populus trichocarpa
XP_002308549
340
37252
Y200
E
G
G
M
R
A
L
Y
R
G
I
G
P
T
L
Maize
Zea mays
P29518
436
46609
Y284
D
E
G
P
S
E
L
Y
R
G
L
T
P
S
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172908
331
36237
Y191
E
G
G
P
R
G
L
Y
R
G
I
G
P
T
L
Baker's Yeast
Sacchar. cerevisiae
P38702
357
40807
Y204
F
C
H
W
C
N
F
Y
R
G
Y
V
P
T
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
96
N.A.
92.7
88.8
N.A.
82.5
81
37
38.2
N.A.
N.A.
50.2
20.2
39.7
Protein Similarity:
100
99.6
N.A.
98.1
N.A.
96.6
92.7
N.A.
87.9
86.7
54.2
53.9
N.A.
N.A.
62
31.6
53.6
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
0
N.A.
93.3
93.3
6.6
0
N.A.
N.A.
6.6
33.3
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
13.3
N.A.
93.3
93.3
6.6
13.3
N.A.
N.A.
26.6
60
6.6
Percent
Protein Identity:
34.4
21.7
N.A.
37.9
37.5
N.A.
Protein Similarity:
54.4
34.8
N.A.
53.6
55.1
N.A.
P-Site Identity:
53.3
40
N.A.
60
40
N.A.
P-Site Similarity:
66.6
60
N.A.
73.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
7
0
7
0
0
0
0
0
7
0
% A
% Cys:
0
7
0
0
7
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% D
% Glu:
50
13
0
7
7
7
0
0
0
7
0
7
0
7
7
% E
% Phe:
7
0
13
38
19
0
50
13
0
0
0
0
7
7
7
% F
% Gly:
0
57
63
0
0
50
0
0
7
69
7
19
13
0
13
% G
% His:
7
0
13
0
0
0
0
0
0
7
7
0
0
0
0
% H
% Ile:
7
7
0
13
0
7
7
7
0
0
25
0
0
0
38
% I
% Lys:
7
0
0
7
0
0
0
7
13
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
13
0
25
0
0
7
44
7
0
7
25
% L
% Met:
7
0
0
7
7
0
0
0
0
7
0
38
0
0
0
% M
% Asn:
0
0
7
0
0
7
0
0
0
0
0
0
0
7
0
% N
% Pro:
0
0
0
13
7
0
0
0
0
0
0
7
69
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
7
0
7
0
25
0
0
0
63
7
0
7
7
0
0
% R
% Ser:
0
13
0
0
13
0
0
0
7
0
0
7
0
7
0
% S
% Thr:
0
0
0
7
7
7
7
0
0
0
0
7
0
57
7
% T
% Val:
0
0
0
0
0
0
7
0
7
0
0
7
0
0
7
% V
% Trp:
0
0
0
13
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
7
7
69
0
0
19
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _