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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A16
All Species:
25.45
Human Site:
Y259
Identified Species:
37.33
UniProt:
P16260
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16260
NP_689920.1
332
36224
Y259
A
I
A
Q
T
I
S
Y
P
F
D
V
T
R
R
Chimpanzee
Pan troglodytes
XP_001168284
332
36249
Y259
A
I
A
Q
T
I
S
Y
P
F
D
V
T
R
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546134
332
36141
Y259
A
I
A
Q
T
I
S
Y
P
F
D
V
T
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0K5
332
36201
Y259
A
I
A
Q
T
I
S
Y
P
F
D
V
T
R
R
Rat
Rattus norvegicus
P16261
322
35038
V252
I
N
L
L
C
G
G
V
A
R
A
I
A
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520566
324
35638
Y251
A
I
A
Q
T
I
S
Y
P
L
D
V
T
R
R
Chicken
Gallus gallus
XP_421570
320
35184
Y247
A
I
A
Q
T
I
S
Y
P
L
D
V
T
R
R
Frog
Xenopus laevis
Q5PQ27
327
36043
R256
P
L
D
V
V
R
R
R
M
Q
T
A
G
V
T
Zebra Danio
Brachydanio rerio
Q0P483
321
35318
A245
A
G
L
I
G
Q
S
A
S
Y
P
L
D
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624199
316
35726
H245
P
L
D
V
T
R
R
H
M
Q
L
G
I
M
H
Nematode Worm
Caenorhab. elegans
Q20799
588
66319
Q471
A
L
V
R
T
R
L
Q
A
L
S
I
T
R
Y
Sea Urchin
Strong. purpuratus
XP_789697
271
30376
G201
I
T
A
N
L
C
V
G
G
L
A
G
A
I
A
Poplar Tree
Populus trichocarpa
XP_002308549
340
37252
Q269
Q
M
Q
V
E
N
L
Q
P
L
S
Q
G
N
A
Maize
Zea mays
P29518
436
46609
Q353
P
L
E
V
A
R
K
Q
M
Q
V
G
A
V
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172908
331
36237
Q261
Q
M
Q
V
E
N
L
Q
P
M
T
S
E
G
N
Baker's Yeast
Sacchar. cerevisiae
P38702
357
40807
Y283
M
A
S
Q
T
A
A
Y
P
F
E
I
I
R
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
96
N.A.
92.7
88.8
N.A.
82.5
81
37
38.2
N.A.
N.A.
50.2
20.2
39.7
Protein Similarity:
100
99.6
N.A.
98.1
N.A.
96.6
92.7
N.A.
87.9
86.7
54.2
53.9
N.A.
N.A.
62
31.6
53.6
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
93.3
93.3
0
13.3
N.A.
N.A.
6.6
26.6
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
93.3
93.3
6.6
26.6
N.A.
N.A.
20
46.6
6.6
Percent
Protein Identity:
34.4
21.7
N.A.
37.9
37.5
N.A.
Protein Similarity:
54.4
34.8
N.A.
53.6
55.1
N.A.
P-Site Identity:
6.6
0
N.A.
6.6
46.6
N.A.
P-Site Similarity:
13.3
6.6
N.A.
13.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
7
44
0
7
7
7
7
13
0
13
7
19
0
13
% A
% Cys:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
0
0
0
0
0
0
38
0
7
0
0
% D
% Glu:
0
0
7
0
13
0
0
0
0
0
7
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
32
0
0
0
0
0
% F
% Gly:
0
7
0
0
7
7
7
7
7
0
0
19
13
7
7
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% H
% Ile:
13
38
0
7
0
38
0
0
0
0
0
19
13
7
0
% I
% Lys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% K
% Leu:
0
25
13
7
7
0
19
0
0
32
7
7
0
0
0
% L
% Met:
7
13
0
0
0
0
0
0
19
7
0
0
0
7
0
% M
% Asn:
0
7
0
7
0
13
0
0
0
0
0
0
0
7
7
% N
% Pro:
19
0
0
0
0
0
0
0
57
0
7
0
0
0
0
% P
% Gln:
13
0
13
44
0
7
0
25
0
19
0
7
0
7
0
% Q
% Arg:
0
0
0
7
0
25
13
7
0
7
0
0
0
50
44
% R
% Ser:
0
0
7
0
0
0
44
0
7
0
13
7
0
0
0
% S
% Thr:
0
7
0
0
57
0
0
0
0
0
13
0
44
0
13
% T
% Val:
0
0
7
32
7
0
7
7
0
0
7
38
0
19
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
44
0
7
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _