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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A16
All Species:
29.7
Human Site:
Y301
Identified Species:
43.56
UniProt:
P16260
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16260
NP_689920.1
332
36224
Y301
H
G
I
R
K
G
L
Y
R
G
L
S
L
N
Y
Chimpanzee
Pan troglodytes
XP_001168284
332
36249
Y301
H
G
I
R
K
G
L
Y
R
G
L
S
L
N
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546134
332
36141
Y301
H
G
I
R
R
G
L
Y
R
G
L
S
L
N
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0K5
332
36201
Y301
H
G
I
R
R
G
L
Y
R
G
L
S
L
N
Y
Rat
Rattus norvegicus
P16261
322
35038
Y294
R
E
T
M
K
Y
V
Y
G
H
H
G
I
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520566
324
35638
Y293
H
G
I
R
R
G
L
Y
R
G
L
S
L
N
Y
Chicken
Gallus gallus
XP_421570
320
35184
Y289
H
G
I
R
R
G
L
Y
R
G
L
S
L
N
Y
Frog
Xenopus laevis
Q5PQ27
327
36043
G298
L
S
M
N
W
V
K
G
P
V
A
V
G
I
S
Zebra Danio
Brachydanio rerio
Q0P483
321
35318
Y287
E
G
I
V
R
G
L
Y
K
G
L
S
M
N
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624199
316
35726
Y287
Y
R
G
M
S
I
N
Y
L
R
A
I
P
M
V
Nematode Worm
Caenorhab. elegans
Q20799
588
66319
I513
T
P
N
F
L
K
V
I
P
A
V
S
I
S
Y
Sea Urchin
Strong. purpuratus
XP_789697
271
30376
P243
I
N
Y
I
R
A
I
P
T
A
A
I
S
F
T
Poplar Tree
Populus trichocarpa
XP_002308549
340
37252
S311
N
Y
I
K
I
V
P
S
V
A
I
G
F
A
A
Maize
Zea mays
P29518
436
46609
L395
L
G
P
S
C
I
K
L
M
P
A
A
G
I
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172908
331
36237
V303
S
I
N
Y
I
K
I
V
P
S
V
A
I
G
F
Baker's Yeast
Sacchar. cerevisiae
P38702
357
40807
G325
F
K
E
R
G
V
R
G
F
F
V
G
L
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
96
N.A.
92.7
88.8
N.A.
82.5
81
37
38.2
N.A.
N.A.
50.2
20.2
39.7
Protein Similarity:
100
99.6
N.A.
98.1
N.A.
96.6
92.7
N.A.
87.9
86.7
54.2
53.9
N.A.
N.A.
62
31.6
53.6
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
13.3
N.A.
93.3
93.3
0
60
N.A.
N.A.
6.6
13.3
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
26.6
N.A.
100
100
6.6
86.6
N.A.
N.A.
13.3
40
13.3
Percent
Protein Identity:
34.4
21.7
N.A.
37.9
37.5
N.A.
Protein Similarity:
54.4
34.8
N.A.
53.6
55.1
N.A.
P-Site Identity:
6.6
6.6
N.A.
0
13.3
N.A.
P-Site Similarity:
26.6
13.3
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
19
25
13
0
7
13
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
7
0
0
7
0
0
0
0
7
7
0
0
7
7
7
% F
% Gly:
0
50
7
0
7
44
0
13
7
44
0
19
13
7
0
% G
% His:
38
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% H
% Ile:
7
7
50
7
13
13
13
7
0
0
7
13
19
13
7
% I
% Lys:
0
7
0
7
19
13
13
0
7
0
0
0
0
0
0
% K
% Leu:
13
0
0
0
7
0
44
7
7
0
44
0
44
0
0
% L
% Met:
0
0
7
13
0
0
0
0
7
0
0
0
7
7
0
% M
% Asn:
7
7
13
7
0
0
7
0
0
0
0
0
0
44
0
% N
% Pro:
0
7
7
0
0
0
7
7
19
7
0
0
7
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
7
0
44
38
0
7
0
38
7
0
0
0
7
7
% R
% Ser:
7
7
0
7
7
0
0
7
0
7
0
50
7
13
7
% S
% Thr:
7
0
7
0
0
0
0
0
7
0
0
0
0
0
7
% T
% Val:
0
0
0
7
0
19
13
7
7
7
19
7
0
0
7
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
7
7
7
7
0
7
0
57
0
0
0
0
0
0
44
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _