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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GLB1 All Species: 10.61
Human Site: Y192 Identified Species: 19.44
UniProt: P16278 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16278 NP_000395.2 677 76075 Y192 V E N E Y G S Y F A C D F D Y
Chimpanzee Pan troglodytes XP_526035 654 74191 N185 I I S I Q V E N E Y G S Y R A
Rhesus Macaque Macaca mulatta XP_001097877 373 42590
Dog Lupus familis XP_851411 651 73709 N184 I I S I Q V E N E Y G S Y R A
Cat Felis silvestris
Mouse Mus musculus P23780 647 73102 P180 L L Y Q N G G P I I T V Q V E
Rat Rattus norvegicus Q5XIL5 631 72305 T164 N P G S N L R T T N K D F I E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514897 656 73205 Y188 V E N E F G S Y F T C D Y N Y
Chicken Gallus gallus NP_001026163 385 43610
Frog Xenopus laevis NP_001121284 645 72749 I176 L Y H N G G P I I S V Q V E N
Zebra Danio Brachydanio rerio NP_001017547 651 72189 E182 I T V Q V E N E Y G S Y F A C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650142 637 71878 N169 M N K Y L Y G N G G P I I M V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792349 657 74597 Y175 V E N E Y G S Y Q T C D H Q Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q93Z24 697 78621 Y222 I E N E Y G S Y G N D K A Y L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.8 52.1 52.5 N.A. 74.1 35.2 N.A. 64.6 42.8 63.9 62.7 N.A. 41.6 N.A. N.A. 53.6
Protein Similarity: 100 64.6 53.6 64.8 N.A. 83.1 52.4 N.A. 77.8 47.8 78.4 76.2 N.A. 58 N.A. N.A. 66.9
P-Site Identity: 100 0 0 0 N.A. 6.6 13.3 N.A. 73.3 0 6.6 6.6 N.A. 0 N.A. N.A. 73.3
P-Site Similarity: 100 20 0 20 N.A. 20 13.3 N.A. 93.3 0 33.3 33.3 N.A. 6.6 N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. 40.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 56.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 8 0 0 8 8 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 24 0 0 0 8 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 8 31 0 8 0 % D
% Glu: 0 31 0 31 0 8 16 8 16 0 0 0 0 8 16 % E
% Phe: 0 0 0 0 8 0 0 0 16 0 0 0 24 0 0 % F
% Gly: 0 0 8 0 8 47 16 0 16 16 16 0 0 0 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 31 16 0 16 0 0 0 8 16 8 0 8 8 8 0 % I
% Lys: 0 0 8 0 0 0 0 0 0 0 8 8 0 0 0 % K
% Leu: 16 8 0 0 8 8 0 0 0 0 0 0 0 0 8 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 8 8 31 8 16 0 8 24 0 16 0 0 0 8 8 % N
% Pro: 0 8 0 0 0 0 8 8 0 0 8 0 0 0 0 % P
% Gln: 0 0 0 16 16 0 0 0 8 0 0 8 8 8 0 % Q
% Arg: 0 0 0 0 0 0 8 0 0 0 0 0 0 16 0 % R
% Ser: 0 0 16 8 0 0 31 0 0 8 8 16 0 0 0 % S
% Thr: 0 8 0 0 0 0 0 8 8 16 8 0 0 0 0 % T
% Val: 24 0 8 0 8 16 0 0 0 0 8 8 8 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 8 8 24 8 0 31 8 16 0 8 24 8 24 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _