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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GLB1 All Species: 0.3
Human Site: Y444 Identified Species: 0.56
UniProt: P16278 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16278 NP_000395.2 677 76075 Y444 N G V H D R A Y V A V D G I P
Chimpanzee Pan troglodytes XP_526035 654 74191 P427 M T H T I F E P T P F W V P N
Rhesus Macaque Macaca mulatta XP_001097877 373 42590 L147 L E K E A I L L R S S D P D Y
Dog Lupus familis XP_851411 651 73709 E425 F L P H P I P E P T Q F W V P
Cat Felis silvestris
Mouse Mus musculus P23780 647 73102 T421 F G Y V L Y R T T L P Q D C S
Rat Rattus norvegicus Q5XIL5 631 72305 K405 D I L P Y L N K P V M L E T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514897 656 73205 P430 E Q V P L S S P F N G V H D R
Chicken Gallus gallus NP_001026163 385 43610 L159 E K W M G V L L P K M K P H L
Frog Xenopus laevis NP_001121284 645 72749 L418 F V L Y R T T L P I N C S N P
Zebra Danio Brachydanio rerio NP_001017547 651 72189 P423 L P V N C V K P T P L S S P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650142 637 71878 G410 E A L G Q Y S G L V L Y E T W
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792349 657 74597 I428 I R D R G Y V I I D Q V W V G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q93Z24 697 78621 G467 S Y I A K K S G N T L R I P K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.8 52.1 52.5 N.A. 74.1 35.2 N.A. 64.6 42.8 63.9 62.7 N.A. 41.6 N.A. N.A. 53.6
Protein Similarity: 100 64.6 53.6 64.8 N.A. 83.1 52.4 N.A. 77.8 47.8 78.4 76.2 N.A. 58 N.A. N.A. 66.9
P-Site Identity: 100 0 6.6 13.3 N.A. 6.6 6.6 N.A. 6.6 0 6.6 6.6 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 0 13.3 20 N.A. 6.6 26.6 N.A. 13.3 6.6 20 20 N.A. 26.6 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 40.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 56.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 8 0 8 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 8 0 8 0 % C
% Asp: 8 0 8 0 8 0 0 0 0 8 0 16 8 16 0 % D
% Glu: 24 8 0 8 0 0 8 8 0 0 0 0 16 0 0 % E
% Phe: 24 0 0 0 0 8 0 0 8 0 8 8 0 0 0 % F
% Gly: 0 16 0 8 16 0 0 16 0 0 8 0 8 0 8 % G
% His: 0 0 8 16 0 0 0 0 0 0 0 0 8 8 0 % H
% Ile: 8 8 8 0 8 16 0 8 8 8 0 0 8 8 0 % I
% Lys: 0 8 8 0 8 8 8 8 0 8 0 8 0 0 8 % K
% Leu: 16 8 24 0 16 8 16 24 8 8 24 8 0 0 16 % L
% Met: 8 0 0 8 0 0 0 0 0 0 16 0 0 0 0 % M
% Asn: 8 0 0 8 0 0 8 0 8 8 8 0 0 8 8 % N
% Pro: 0 8 8 16 8 0 8 24 31 16 8 0 16 24 31 % P
% Gln: 0 8 0 0 8 0 0 0 0 0 16 8 0 0 0 % Q
% Arg: 0 8 0 8 8 8 8 0 8 0 0 8 0 0 8 % R
% Ser: 8 0 0 0 0 8 24 0 0 8 8 8 16 0 8 % S
% Thr: 0 8 0 8 0 8 8 8 24 16 0 0 0 16 0 % T
% Val: 0 8 24 8 0 16 8 0 8 16 8 16 8 16 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 8 16 0 8 % W
% Tyr: 0 8 8 8 8 24 0 8 0 0 0 8 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _