KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3CB
All Species:
34.85
Human Site:
S455
Identified Species:
54.76
UniProt:
P16298
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16298
NP_001135826.1
524
59024
S455
G
G
R
Q
T
L
Q
S
A
T
V
E
A
I
E
Chimpanzee
Pan troglodytes
XP_001142700
534
60207
S465
G
G
R
Q
T
L
Q
S
A
T
V
E
A
I
E
Rhesus Macaque
Macaca mulatta
XP_001101616
524
59006
S455
G
G
R
Q
T
L
Q
S
A
T
V
E
A
I
E
Dog
Lupus familis
XP_850935
524
59010
S455
G
G
R
Q
T
L
Q
S
A
T
V
E
A
I
E
Cat
Felis silvestris
Mouse
Mus musculus
P48453
525
59155
S456
G
G
R
Q
T
L
Q
S
A
T
V
E
A
I
E
Rat
Rattus norvegicus
P20651
525
59095
S456
G
G
R
Q
T
L
Q
S
A
T
V
E
A
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505489
437
49430
G381
E
A
E
K
A
I
R
G
F
S
P
Q
H
R
I
Chicken
Gallus gallus
P48463
309
35545
R254
G
Y
N
W
C
H
D
R
N
V
V
T
I
F
S
Frog
Xenopus laevis
NP_001080813
518
58366
S446
G
G
K
Q
T
L
Q
S
A
T
V
E
A
I
E
Zebra Danio
Brachydanio rerio
NP_001017856
511
57796
S436
G
G
K
Q
T
L
Q
S
A
T
I
E
A
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27889
570
63082
N514
G
G
K
Q
S
L
K
N
A
M
Q
G
F
S
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTT8
321
36288
T266
H
F
R
K
R
V
V
T
V
W
S
A
P
N
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48486
322
36548
P267
L
V
T
I
F
S
A
P
N
Y
C
G
E
F
D
Baker's Yeast
Sacchar. cerevisiae
P14747
604
68509
S546
V
L
P
R
G
A
L
S
N
G
V
K
G
L
D
Red Bread Mold
Neurospora crassa
Q05681
558
63895
A499
G
A
E
G
I
K
N
A
I
S
S
F
E
D
A
Conservation
Percent
Protein Identity:
100
98.1
99.6
99.6
N.A.
99
98.8
N.A.
81.8
27.6
81.8
81.4
N.A.
69.4
N.A.
29.7
N.A.
Protein Similarity:
100
98.1
100
100
N.A.
99.4
99.2
N.A.
82.8
38.5
91.5
89.6
N.A.
77.3
N.A.
39.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
13.3
93.3
86.6
N.A.
33.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
13.3
100
100
N.A.
60
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
42.7
52.1
Protein Similarity:
N.A.
N.A.
N.A.
40.8
57.6
64.7
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
40
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
0
7
7
7
7
60
0
0
7
54
0
7
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
14
% D
% Glu:
7
0
14
0
0
0
0
0
0
0
0
54
14
0
54
% E
% Phe:
0
7
0
0
7
0
0
0
7
0
0
7
7
14
0
% F
% Gly:
74
60
0
7
7
0
0
7
0
7
0
14
7
0
0
% G
% His:
7
0
0
0
0
7
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
7
7
7
0
0
7
0
7
0
7
54
7
% I
% Lys:
0
0
20
14
0
7
7
0
0
0
0
7
0
0
0
% K
% Leu:
7
7
0
0
0
60
7
0
0
0
0
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
7
7
20
0
0
0
0
7
0
% N
% Pro:
0
0
7
0
0
0
0
7
0
0
7
0
7
0
7
% P
% Gln:
0
0
0
60
0
0
54
0
0
0
7
7
0
0
0
% Q
% Arg:
0
0
47
7
7
0
7
7
0
0
0
0
0
7
0
% R
% Ser:
0
0
0
0
7
7
0
60
0
14
14
0
0
7
7
% S
% Thr:
0
0
7
0
54
0
0
7
0
54
0
7
0
0
0
% T
% Val:
7
7
0
0
0
7
7
0
7
7
60
0
0
0
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _