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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3CB
All Species:
26.36
Human Site:
S471
Identified Species:
41.43
UniProt:
P16298
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16298
NP_001135826.1
524
59024
S471
E
K
A
I
R
G
F
S
P
P
H
R
I
C
S
Chimpanzee
Pan troglodytes
XP_001142700
534
60207
S481
E
K
A
I
R
G
F
S
P
P
H
R
I
C
S
Rhesus Macaque
Macaca mulatta
XP_001101616
524
59006
S471
E
K
A
I
R
G
F
S
P
P
H
R
I
C
S
Dog
Lupus familis
XP_850935
524
59010
S471
E
K
A
I
R
G
F
S
P
P
H
R
I
C
S
Cat
Felis silvestris
Mouse
Mus musculus
P48453
525
59155
S472
E
K
A
I
R
G
F
S
P
P
H
R
I
C
S
Rat
Rattus norvegicus
P20651
525
59095
S472
E
K
A
I
R
G
S
S
P
P
H
R
I
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505489
437
49430
L397
S
F
E
E
A
K
G
L
D
R
I
N
E
R
M
Chicken
Gallus gallus
P48463
309
35545
G270
P
N
Y
C
Y
R
C
G
N
Q
A
A
I
M
E
Frog
Xenopus laevis
NP_001080813
518
58366
S462
D
E
A
I
K
G
F
S
P
Q
H
K
I
T
S
Zebra Danio
Brachydanio rerio
NP_001017856
511
57796
E452
V
E
E
V
K
D
G
E
A
I
R
G
F
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27889
570
63082
E530
H
K
I
T
S
F
A
E
A
K
G
L
D
A
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTT8
321
36288
A282
Y
R
C
G
N
V
A
A
I
M
E
V
T
E
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48486
322
36548
D283
A
G
A
L
M
S
V
D
D
S
L
T
C
S
F
Baker's Yeast
Sacchar. cerevisiae
P14747
604
68509
A562
A
L
S
T
F
E
R
A
R
K
H
D
L
I
N
Red Bread Mold
Neurospora crassa
Q05681
558
63895
R515
K
V
D
L
Q
N
E
R
L
P
P
S
H
D
E
Conservation
Percent
Protein Identity:
100
98.1
99.6
99.6
N.A.
99
98.8
N.A.
81.8
27.6
81.8
81.4
N.A.
69.4
N.A.
29.7
N.A.
Protein Similarity:
100
98.1
100
100
N.A.
99.4
99.2
N.A.
82.8
38.5
91.5
89.6
N.A.
77.3
N.A.
39.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
0
6.6
60
0
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
0
6.6
86.6
20
N.A.
6.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
42.7
52.1
Protein Similarity:
N.A.
N.A.
N.A.
40.8
57.6
64.7
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
54
0
7
0
14
14
14
0
7
7
0
7
0
% A
% Cys:
0
0
7
7
0
0
7
0
0
0
0
0
7
40
0
% C
% Asp:
7
0
7
0
0
7
0
7
14
0
0
7
7
7
0
% D
% Glu:
40
14
14
7
0
7
7
14
0
0
7
0
7
7
20
% E
% Phe:
0
7
0
0
7
7
40
0
0
0
0
0
7
0
7
% F
% Gly:
0
7
0
7
0
47
14
7
0
0
7
7
0
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
54
0
7
0
0
% H
% Ile:
0
0
7
47
0
0
0
0
7
7
7
0
54
7
0
% I
% Lys:
7
47
0
0
14
7
0
0
0
14
0
7
0
0
0
% K
% Leu:
0
7
0
14
0
0
0
7
7
0
7
7
7
0
0
% L
% Met:
0
0
0
0
7
0
0
0
0
7
0
0
0
7
7
% M
% Asn:
0
7
0
0
7
7
0
0
7
0
0
7
0
0
7
% N
% Pro:
7
0
0
0
0
0
0
0
47
47
7
0
0
0
7
% P
% Gln:
0
0
0
0
7
0
0
0
0
14
0
0
0
0
0
% Q
% Arg:
0
7
0
0
40
7
7
7
7
7
7
40
0
7
0
% R
% Ser:
7
0
7
0
7
7
7
47
0
7
0
7
0
14
47
% S
% Thr:
0
0
0
14
0
0
0
0
0
0
0
7
7
7
0
% T
% Val:
7
7
0
7
0
7
7
0
0
0
0
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _