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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3CB
All Species:
42.42
Human Site:
Y179
Identified Species:
66.67
UniProt:
P16298
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16298
NP_001135826.1
524
59024
Y179
K
Q
E
C
K
I
K
Y
S
E
R
V
Y
E
A
Chimpanzee
Pan troglodytes
XP_001142700
534
60207
Y179
K
Q
E
C
K
I
K
Y
S
E
R
V
Y
E
A
Rhesus Macaque
Macaca mulatta
XP_001101616
524
59006
Y179
K
Q
E
C
K
I
K
Y
S
E
R
V
Y
E
A
Dog
Lupus familis
XP_850935
524
59010
Y179
K
Q
E
C
K
I
K
Y
S
E
R
V
Y
E
A
Cat
Felis silvestris
Mouse
Mus musculus
P48453
525
59155
Y179
K
Q
E
C
K
I
K
Y
S
E
R
V
Y
E
A
Rat
Rattus norvegicus
P20651
525
59095
Y179
K
Q
E
C
K
I
K
Y
S
E
R
V
Y
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505489
437
49430
E126
V
H
G
G
L
S
P
E
I
H
T
L
D
D
I
Chicken
Gallus gallus
P48463
309
35545
Frog
Xenopus laevis
NP_001080813
518
58366
Y170
K
Q
E
C
K
I
K
Y
S
E
R
I
Y
D
A
Zebra Danio
Brachydanio rerio
NP_001017856
511
57796
Y159
K
Q
E
C
K
I
K
Y
S
E
Q
V
Y
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27889
570
63082
Y236
K
Q
E
C
K
I
K
Y
S
E
R
V
Y
D
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTT8
321
36288
L12
D
A
A
G
P
D
Q
L
G
P
N
D
L
D
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48486
322
36548
L13
L
D
D
I
I
R
R
L
L
A
T
N
N
G
R
Baker's Yeast
Sacchar. cerevisiae
P14747
604
68509
Y224
K
N
E
M
L
H
K
Y
N
L
D
I
Y
E
K
Red Bread Mold
Neurospora crassa
Q05681
558
63895
Y208
K
L
E
C
K
H
K
Y
S
E
A
I
Y
E
A
Conservation
Percent
Protein Identity:
100
98.1
99.6
99.6
N.A.
99
98.8
N.A.
81.8
27.6
81.8
81.4
N.A.
69.4
N.A.
29.7
N.A.
Protein Similarity:
100
98.1
100
100
N.A.
99.4
99.2
N.A.
82.8
38.5
91.5
89.6
N.A.
77.3
N.A.
39.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
0
86.6
86.6
N.A.
93.3
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
0
100
100
N.A.
100
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
42.7
52.1
Protein Similarity:
N.A.
N.A.
N.A.
40.8
57.6
64.7
P-Site Identity:
N.A.
N.A.
N.A.
0
40
73.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
53.3
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
0
0
0
0
7
7
0
0
0
67
% A
% Cys:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
7
0
0
7
0
0
0
0
7
7
7
34
0
% D
% Glu:
0
0
74
0
0
0
0
7
0
67
0
0
0
54
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
14
0
0
0
0
7
0
0
0
0
7
0
% G
% His:
0
7
0
0
0
14
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
7
7
60
0
0
7
0
0
20
0
0
7
% I
% Lys:
74
0
0
0
67
0
74
0
0
0
0
0
0
0
7
% K
% Leu:
7
7
0
0
14
0
0
14
7
7
0
7
7
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
7
0
7
7
7
0
0
% N
% Pro:
0
0
0
0
7
0
7
0
0
7
0
0
0
0
0
% P
% Gln:
0
60
0
0
0
0
7
0
0
0
7
0
0
0
0
% Q
% Arg:
0
0
0
0
0
7
7
0
0
0
54
0
0
0
14
% R
% Ser:
0
0
0
0
0
7
0
0
67
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
14
0
0
0
0
% T
% Val:
7
0
0
0
0
0
0
0
0
0
0
54
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
74
0
0
0
0
74
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _