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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNA2 All Species: 33.03
Human Site: T219 Identified Species: 72.67
UniProt: P16389 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16389 NP_004965.1 499 56717 T219 Y Q Q S T S F T D P F F I V E
Chimpanzee Pan troglodytes XP_522328 495 56433 T218 I Y N S N I F T D P F F I V E
Rhesus Macaque Macaca mulatta XP_001101471 499 56668 T219 Y Q Q S T S F T D P F F I V E
Dog Lupus familis XP_543859 495 56374 T218 I Y N S N I F T D P F F I V E
Cat Felis silvestris
Mouse Mus musculus P16388 495 56391 T218 I Y T S N I F T D P F F I V E
Rat Rattus norvegicus P63142 499 56682 T219 Y Q Q S T S F T D P F F I V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508339 499 56706 T219 Y Q Q T T S F T D P F F I V E
Chicken Gallus gallus Q7T199 516 58965 M240 I S I I I F C M E T L P E F R
Frog Xenopus laevis P22739 499 56683 T219 F Q K S N T F T D P F F I V E
Zebra Danio Brachydanio rerio NP_001104640 495 56362 T215 S Y T S T Y F T D P F F I L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08510 655 74175 T276 E D E V P D I T D P F F L I E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.5 99.8 81.1 N.A. 80.5 99.4 N.A. 98.8 63.5 91.1 91.9 N.A. 52.2 N.A. N.A. N.A.
Protein Similarity: 100 87.7 99.8 87.9 N.A. 87.7 99.5 N.A. 99.4 74.4 95.9 94.3 N.A. 62.5 N.A. N.A. N.A.
P-Site Identity: 100 66.6 100 66.6 N.A. 66.6 100 N.A. 93.3 0 73.3 66.6 N.A. 40 N.A. N.A. N.A.
P-Site Similarity: 100 66.6 100 66.6 N.A. 66.6 100 N.A. 100 6.6 93.3 73.3 N.A. 60 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 10 0 0 91 0 0 0 0 0 0 % D
% Glu: 10 0 10 0 0 0 0 0 10 0 0 0 10 0 91 % E
% Phe: 10 0 0 0 0 10 82 0 0 0 91 91 0 10 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 37 0 10 10 10 28 10 0 0 0 0 0 82 10 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 10 0 10 10 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 19 0 37 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 0 91 0 10 0 0 0 % P
% Gln: 0 46 37 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 10 10 0 73 0 37 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 19 10 46 10 0 91 0 10 0 0 0 0 0 % T
% Val: 0 0 0 10 0 0 0 0 0 0 0 0 0 73 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 37 37 0 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _