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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNA2
All Species:
26.06
Human Site:
T421
Identified Species:
57.33
UniProt:
P16389
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16389
NP_004965.1
499
56717
T421
N
Y
F
Y
H
R
E
T
E
G
E
E
Q
A
Q
Chimpanzee
Pan troglodytes
XP_522328
495
56433
R417
N
F
N
Y
F
Y
H
R
E
T
E
G
E
E
Q
Rhesus Macaque
Macaca mulatta
XP_001101471
499
56668
T421
N
Y
F
Y
H
R
E
T
E
G
E
E
Q
A
Q
Dog
Lupus familis
XP_543859
495
56374
R417
N
F
N
Y
F
Y
H
R
E
T
E
G
E
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
P16388
495
56391
R417
N
F
N
Y
F
Y
H
R
E
T
E
G
E
E
Q
Rat
Rattus norvegicus
P63142
499
56682
T421
N
Y
F
Y
H
R
E
T
E
G
E
E
Q
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508339
499
56706
T421
N
Y
F
Y
H
R
E
T
E
G
E
E
Q
A
Q
Chicken
Gallus gallus
Q7T199
516
58965
C433
T
V
G
Y
G
D
M
C
P
T
T
L
G
G
K
Frog
Xenopus laevis
P22739
499
56683
T421
N
Y
F
Y
H
R
E
T
E
G
E
E
Q
A
Q
Zebra Danio
Brachydanio rerio
NP_001104640
495
56362
T417
N
Y
F
Y
H
R
E
T
E
G
E
E
Q
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08510
655
74175
T489
N
Y
F
Y
H
R
E
T
D
Q
E
E
M
Q
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.5
99.8
81.1
N.A.
80.5
99.4
N.A.
98.8
63.5
91.1
91.9
N.A.
52.2
N.A.
N.A.
N.A.
Protein Similarity:
100
87.7
99.8
87.9
N.A.
87.7
99.5
N.A.
99.4
74.4
95.9
94.3
N.A.
62.5
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
100
33.3
N.A.
33.3
100
N.A.
100
6.6
100
100
N.A.
66.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
100
46.6
N.A.
46.6
100
N.A.
100
13.3
100
100
N.A.
73.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
55
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
64
0
82
0
91
64
28
28
0
% E
% Phe:
0
28
64
0
28
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
10
0
0
0
0
55
0
28
10
10
0
% G
% His:
0
0
0
0
64
0
28
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% M
% Asn:
91
0
28
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
55
10
82
% Q
% Arg:
0
0
0
0
0
64
0
28
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% S
% Thr:
10
0
0
0
0
0
0
64
0
37
10
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
64
0
100
0
28
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _