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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST1H1D
All Species:
11.82
Human Site:
S174
Identified Species:
26
UniProt:
P16402
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16402
NP_005311.1
221
22350
S174
G
T
K
K
V
A
K
S
A
K
K
V
K
T
P
Chimpanzee
Pan troglodytes
XP_001172808
221
22291
S174
G
T
K
K
V
A
K
S
A
K
K
V
K
T
P
Rhesus Macaque
Macaca mulatta
P40286
208
22075
T159
R
A
K
K
P
R
A
T
A
P
K
K
A
V
R
Dog
Lupus familis
XP_853847
290
29282
S228
V
T
K
K
V
A
K
S
P
K
K
E
K
A
A
Cat
Felis silvestris
Mouse
Mus musculus
P43274
219
21959
P173
G
A
K
K
A
K
S
P
K
K
A
K
A
T
K
Rat
Rattus norvegicus
P15865
219
21969
P173
G
A
K
K
A
K
S
P
K
K
A
K
A
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515094
223
22581
S175
A
T
K
K
A
T
K
S
P
R
K
T
K
T
A
Chicken
Gallus gallus
P08284
219
22026
P172
T
K
K
A
A
K
S
P
K
K
A
A
K
A
G
Frog
Xenopus laevis
P06892
210
21355
K163
A
A
A
K
S
P
K
K
L
K
K
P
A
K
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02255
256
26341
K165
A
V
G
A
A
D
K
K
P
K
A
K
K
A
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P19375
205
22145
K160
T
E
K
K
E
K
K
K
T
P
K
K
A
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
51.1
56.2
N.A.
83.2
83.7
N.A.
75.7
69.6
58.8
N.A.
N.A.
37.5
N.A.
N.A.
38.9
Protein Similarity:
100
99
64.7
62
N.A.
85.5
86.4
N.A.
82.9
75.5
64.7
N.A.
N.A.
48.4
N.A.
N.A.
50.2
P-Site Identity:
100
100
26.6
66.6
N.A.
33.3
33.3
N.A.
53.3
20
26.6
N.A.
N.A.
20
N.A.
N.A.
26.6
P-Site Similarity:
100
100
33.3
66.6
N.A.
33.3
33.3
N.A.
60
20
26.6
N.A.
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
37
10
19
46
28
10
0
28
0
37
10
46
28
28
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
10
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
37
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
82
82
0
37
64
28
28
73
64
46
55
10
28
% K
% Leu:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
10
0
28
28
19
0
10
0
10
19
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
10
0
0
0
10
0
0
0
0
10
% R
% Ser:
0
0
0
0
10
0
28
37
0
0
0
0
0
0
0
% S
% Thr:
19
37
0
0
0
10
0
10
10
0
0
10
0
46
0
% T
% Val:
10
10
0
0
28
0
0
0
0
0
0
19
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _