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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIST1H1D All Species: 21.82
Human Site: S59 Identified Species: 48
UniProt: P16402 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16402 NP_005311.1 221 22350 S59 S K E R S G V S L A A L K K A
Chimpanzee Pan troglodytes XP_001172808 221 22291 S59 S K E R S G V S L A A L K K A
Rhesus Macaque Macaca mulatta P40286 208 22075 S62 S Q E R V G M S L A A L K K A
Dog Lupus familis XP_853847 290 29282 S113 S K E R S G V S L A A L K K A
Cat Felis silvestris
Mouse Mus musculus P43274 219 21959 L59 K E R S G V S L A A L K K A L
Rat Rattus norvegicus P15865 219 21969 L59 K E R S G V S L A A L K K A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515094 223 22581 L59 K E R N G V S L A A L K K A L
Chicken Gallus gallus P08284 219 22026 S59 S K E R K G L S L A A L K K A
Frog Xenopus laevis P06892 210 21355 S64 S K E R S G V S L A A L K K T
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P02255 256 26341 L68 K E R G G S S L L A I K K Y I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P19375 205 22145 F61 Q M D R Q L L F I K R A L K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 51.1 56.2 N.A. 83.2 83.7 N.A. 75.7 69.6 58.8 N.A. N.A. 37.5 N.A. N.A. 38.9
Protein Similarity: 100 99 64.7 62 N.A. 85.5 86.4 N.A. 82.9 75.5 64.7 N.A. N.A. 48.4 N.A. N.A. 50.2
P-Site Identity: 100 100 80 100 N.A. 13.3 13.3 N.A. 13.3 86.6 93.3 N.A. N.A. 20 N.A. N.A. 13.3
P-Site Similarity: 100 100 93.3 100 N.A. 20 20 N.A. 20 93.3 93.3 N.A. N.A. 26.6 N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 28 91 55 10 0 28 46 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 37 55 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 37 55 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 10 % I
% Lys: 37 46 0 0 10 0 0 0 0 10 0 37 91 64 0 % K
% Leu: 0 0 0 0 0 10 19 37 64 0 28 55 10 0 28 % L
% Met: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 37 64 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 55 0 0 19 37 10 37 55 0 0 0 0 0 0 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 10 28 37 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _