KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST1H1C
All Species:
17.88
Human Site:
T146
Identified Species:
39.33
UniProt:
P16403
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16403
NP_005310.1
213
21365
T146
K
K
A
A
G
G
A
T
P
K
K
S
A
K
K
Chimpanzee
Pan troglodytes
XP_001172525
213
21376
T146
K
K
A
A
G
G
A
T
P
K
K
S
A
K
K
Rhesus Macaque
Macaca mulatta
P40286
208
22075
K155
K
T
N
K
R
A
K
K
P
R
A
T
A
P
K
Dog
Lupus familis
XP_853847
290
29282
T201
K
K
A
A
G
T
G
T
P
K
K
S
A
K
K
Cat
Felis silvestris
Mouse
Mus musculus
P43274
219
21959
T146
K
K
A
A
G
T
A
T
A
K
K
S
T
K
K
Rat
Rattus norvegicus
P15865
219
21969
T146
K
K
A
T
G
T
A
T
P
K
K
S
T
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515094
223
22581
G148
P
K
K
P
A
A
S
G
A
K
R
S
V
K
K
Chicken
Gallus gallus
P08284
219
22026
K145
A
A
A
A
K
K
P
K
K
A
A
A
V
K
K
Frog
Xenopus laevis
P06892
210
21355
K152
A
K
S
P
K
K
P
K
K
V
S
A
A
A
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02255
256
26341
K198
A
K
K
T
G
I
I
K
S
K
P
A
A
T
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P19375
205
22145
T153
K
K
P
V
K
K
T
T
E
K
K
E
K
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
50.7
56.9
N.A.
83.5
84
N.A.
74.4
69.4
58.6
N.A.
N.A.
42.5
N.A.
N.A.
39.4
Protein Similarity:
100
99.5
61.9
60.6
N.A.
84
84.4
N.A.
79.8
73.9
67.1
N.A.
N.A.
52.3
N.A.
N.A.
49.3
P-Site Identity:
100
100
26.6
86.6
N.A.
80
80
N.A.
33.3
26.6
20
N.A.
N.A.
33.3
N.A.
N.A.
46.6
P-Site Similarity:
100
100
40
86.6
N.A.
80
80
N.A.
46.6
33.3
33.3
N.A.
N.A.
40
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
10
55
46
10
19
37
0
19
10
19
28
55
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
55
19
10
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% I
% Lys:
64
82
19
10
28
28
10
37
19
73
55
0
10
73
100
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
10
19
0
0
19
0
46
0
10
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
10
10
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
10
0
10
0
10
55
0
0
0
% S
% Thr:
0
10
0
19
0
28
10
55
0
0
0
10
19
10
0
% T
% Val:
0
0
0
10
0
0
0
0
0
10
0
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _