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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIST1H1C All Species: 30.61
Human Site: T154 Identified Species: 67.33
UniProt: P16403 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16403 NP_005310.1 213 21365 T154 P K K S A K K T P K K A K K P
Chimpanzee Pan troglodytes XP_001172525 213 21376 T154 P K K S A K K T P K K A K K P
Rhesus Macaque Macaca mulatta P40286 208 22075 K163 P R A T A P K K A V R S G R K
Dog Lupus familis XP_853847 290 29282 T209 P K K S A K K T P K K A K K P
Cat Felis silvestris
Mouse Mus musculus P43274 219 21959 T154 A K K S T K K T P K K A K K P
Rat Rattus norvegicus P15865 219 21969 T154 P K K S T K K T P K K A K K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515094 223 22581 T156 A K R S V K K T P K K A K K P
Chicken Gallus gallus P08284 219 22026 S153 K A A A V K K S P K K A K K P
Frog Xenopus laevis P06892 210 21355 S160 K V S A A A K S P K K L K K P
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P02255 256 26341 A206 S K P A A T K A K V T A A K P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P19375 205 22145 T161 E K K E K K K T P K K A P K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 50.7 56.9 N.A. 83.5 84 N.A. 74.4 69.4 58.6 N.A. N.A. 42.5 N.A. N.A. 39.4
Protein Similarity: 100 99.5 61.9 60.6 N.A. 84 84.4 N.A. 79.8 73.9 67.1 N.A. N.A. 52.3 N.A. N.A. 49.3
P-Site Identity: 100 100 20 100 N.A. 86.6 93.3 N.A. 80 60 53.3 N.A. N.A. 40 N.A. N.A. 66.6
P-Site Similarity: 100 100 53.3 100 N.A. 86.6 93.3 N.A. 86.6 73.3 66.6 N.A. N.A. 46.6 N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 10 19 28 55 10 0 10 10 0 0 82 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 19 73 55 0 10 73 100 10 10 82 82 0 73 91 19 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 46 0 10 0 0 10 0 0 82 0 0 0 10 0 82 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 10 0 0 0 0 0 0 0 10 0 0 10 0 % R
% Ser: 10 0 10 55 0 0 0 19 0 0 0 10 0 0 0 % S
% Thr: 0 0 0 10 19 10 0 64 0 0 10 0 0 0 0 % T
% Val: 0 10 0 0 19 0 0 0 0 19 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _