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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST1H1C
All Species:
36.36
Human Site:
Y71
Identified Species:
80
UniProt:
P16403
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16403
NP_005310.1
213
21365
Y71
K
A
L
A
A
A
G
Y
D
V
E
K
N
N
S
Chimpanzee
Pan troglodytes
XP_001172525
213
21376
Y71
K
A
L
A
A
A
G
Y
D
V
E
K
N
N
S
Rhesus Macaque
Macaca mulatta
P40286
208
22075
Y75
K
A
L
A
A
A
G
Y
D
V
E
K
N
N
S
Dog
Lupus familis
XP_853847
290
29282
Y126
K
A
L
A
A
A
G
Y
D
V
E
K
N
N
S
Cat
Felis silvestris
Mouse
Mus musculus
P43274
219
21959
Y71
K
A
L
A
A
A
G
Y
D
V
E
K
N
N
S
Rat
Rattus norvegicus
P15865
219
21969
Y71
K
A
L
A
A
A
G
Y
D
V
E
K
N
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515094
223
22581
Y71
K
A
L
A
A
A
G
Y
D
V
E
K
N
N
S
Chicken
Gallus gallus
P08284
219
22026
Y72
K
A
L
A
A
G
G
Y
D
V
E
K
N
N
S
Frog
Xenopus laevis
P06892
210
21355
Y77
K
T
L
A
A
G
G
Y
D
V
D
K
N
N
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02255
256
26341
C81
Y
I
T
A
T
Y
K
C
D
A
Q
K
L
A
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P19375
205
22145
T78
E
K
G
K
L
V
Q
T
K
G
K
G
A
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
50.7
56.9
N.A.
83.5
84
N.A.
74.4
69.4
58.6
N.A.
N.A.
42.5
N.A.
N.A.
39.4
Protein Similarity:
100
99.5
61.9
60.6
N.A.
84
84.4
N.A.
79.8
73.9
67.1
N.A.
N.A.
52.3
N.A.
N.A.
49.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
80
N.A.
N.A.
20
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
86.6
N.A.
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
73
0
91
82
64
0
0
0
10
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
91
0
10
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
73
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
19
82
0
0
10
0
10
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
82
10
0
10
0
0
10
0
10
0
10
91
0
0
0
% K
% Leu:
0
0
82
0
10
0
0
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
82
82
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
82
% S
% Thr:
0
10
10
0
10
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
82
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
10
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _