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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPCAM
All Species:
24.55
Human Site:
Y297
Identified Species:
77.14
UniProt:
P16422
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16422
NP_002345.2
314
34932
Y297
R
K
K
R
M
A
K
Y
E
K
A
E
I
K
E
Chimpanzee
Pan troglodytes
XP_515458
416
46003
Y399
R
K
K
R
M
A
K
Y
E
K
A
E
I
K
E
Rhesus Macaque
Macaca mulatta
Q1WER1
314
34861
Y297
R
K
K
R
M
A
K
Y
E
K
A
E
I
K
E
Dog
Lupus familis
XP_538481
459
51105
Y442
R
K
N
R
M
A
K
Y
E
K
A
E
I
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99JW5
315
35000
Y298
T
R
K
K
S
A
K
Y
E
K
A
E
I
K
E
Rat
Rattus norvegicus
O55159
315
35189
Y298
T
R
K
R
S
A
K
Y
E
K
A
E
I
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516292
129
14523
E122
A
E
I
K
E
M
G
E
M
R
R
E
F
N
S
Chicken
Gallus gallus
Q5F381
306
34341
Y289
S
R
R
R
K
G
K
Y
V
K
A
E
M
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.8
93.9
54.9
N.A.
81.2
81.5
N.A.
30.2
56.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
73.5
98
61.6
N.A.
88.8
88.5
N.A.
37.2
72.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
73.3
80
N.A.
6.6
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
26.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
0
75
0
0
0
0
88
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
13
0
0
13
0
0
13
75
0
0
100
0
0
88
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% F
% Gly:
0
0
0
0
0
13
13
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
13
0
0
0
0
0
0
0
0
0
75
0
0
% I
% Lys:
0
50
63
25
13
0
88
0
0
88
0
0
0
88
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
50
13
0
0
13
0
0
0
13
0
0
% M
% Asn:
0
0
13
0
0
0
0
0
0
0
0
0
0
13
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
50
38
13
75
0
0
0
0
0
13
13
0
0
0
0
% R
% Ser:
13
0
0
0
25
0
0
0
0
0
0
0
0
0
13
% S
% Thr:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
88
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _