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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POR All Species: 18.79
Human Site: S124 Identified Species: 34.44
UniProt: P16435 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16435 NP_000932.3 677 76690 S124 Y D L A D L S S L P E I D N A
Chimpanzee Pan troglodytes XP_519157 686 77690 S133 Y D L A D L S S L P E I D N A
Rhesus Macaque Macaca mulatta XP_001109664 680 76966 S127 Y D L A D L S S L P E I D N A
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P37040 678 77025 S124 Y D L A D L S S L P E I D K S
Rat Rattus norvegicus P00388 678 76944 S124 Y D L A D L S S L P E I D K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90703 1136 129631 I574 L C M D E Y N I S D L E K E T
Frog Xenopus laevis Q6NRG5 600 68059 K111 K F N F I A K K L H K R L N Q
Zebra Danio Brachydanio rerio Q6PFP6 595 66871 N106 D S S Y P K F N F V A K K L H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27597 679 76328 Q128 C D M E E L L Q L K D I D N S
Honey Bee Apis mellifera XP_001119949 694 79008 H143 C D M E E L I H L K T I P N S
Nematode Worm Caenorhab. elegans NP_498103 662 75190 A124 R L S E V E D A L L V L C I A
Sea Urchin Strong. purpuratus XP_799192 590 66343 S101 T G T G E E F S V R L A K E A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P16603 691 76753 V128 G D F P D G A V N F E D F I C
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 98.8 N.A. N.A. 92 92.4 N.A. N.A. 20.7 27.4 27.7 N.A. 56.8 57.4 47.2 51.4
Protein Similarity: 100 97 99.5 N.A. N.A. 96.3 96.7 N.A. N.A. 36 46.3 46 N.A. 75.5 74.6 65.7 67.9
P-Site Identity: 100 100 100 N.A. N.A. 86.6 86.6 N.A. N.A. 0 13.3 0 N.A. 40 33.3 13.3 13.3
P-Site Similarity: 100 100 100 N.A. N.A. 93.3 93.3 N.A. N.A. 20 20 6.6 N.A. 66.6 53.3 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 54.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 39 0 8 8 8 0 0 8 8 0 0 39 % A
% Cys: 16 8 0 0 0 0 0 0 0 0 0 0 8 0 8 % C
% Asp: 8 62 0 8 47 0 8 0 0 8 8 8 47 0 0 % D
% Glu: 0 0 0 24 31 16 0 0 0 0 47 8 0 16 0 % E
% Phe: 0 8 8 8 0 0 16 0 8 8 0 0 8 0 0 % F
% Gly: 8 8 0 8 0 8 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 8 % H
% Ile: 0 0 0 0 8 0 8 8 0 0 0 54 0 16 0 % I
% Lys: 8 0 0 0 0 8 8 8 0 16 8 8 24 16 0 % K
% Leu: 8 8 39 0 0 54 8 0 70 8 16 8 8 8 0 % L
% Met: 0 0 24 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 8 8 8 0 0 0 0 47 0 % N
% Pro: 0 0 0 8 8 0 0 0 0 39 0 0 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % Q
% Arg: 8 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % R
% Ser: 0 8 16 0 0 0 39 47 8 0 0 0 0 0 31 % S
% Thr: 8 0 8 0 0 0 0 0 0 0 8 0 0 0 8 % T
% Val: 0 0 0 0 8 0 0 8 8 8 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 39 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _