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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POR All Species: 20.61
Human Site: S569 Identified Species: 37.78
UniProt: P16435 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16435 NP_000932.3 677 76690 S569 L Y Y G C R R S D E D Y L Y R
Chimpanzee Pan troglodytes XP_519157 686 77690 S578 L Y Y G C R R S D E D Y L Y R
Rhesus Macaque Macaca mulatta XP_001109664 680 76966 S572 L Y Y G C R R S D E D Y L Y R
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P37040 678 77025 S569 L Y Y G C R R S D E D Y L Y R
Rat Rattus norvegicus P00388 678 76944 S569 L Y Y G C R R S D E D Y L Y R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90703 1136 129631 P1016 L L F G C R H P D M D H I Y K
Frog Xenopus laevis Q6NRG5 600 68059 E503 F Y F E K E W E D L G N R G Y
Zebra Danio Brachydanio rerio Q6PFP6 595 66871 Q498 F Y C G S E W Q E K V Q A G Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27597 679 76328 R571 L Y F G C R K R S E D Y I Y E
Honey Bee Apis mellifera XP_001119949 694 79008 K586 L Y F G C R K K D E D F L Y K
Nematode Worm Caenorhab. elegans NP_498103 662 75190 P554 L Y Y G C R H P D H D Y I Y K
Sea Urchin Strong. purpuratus XP_799192 590 66343 D493 Y I Y K D E L D E Y L K N G T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P16603 691 76753 T583 L F Y G S R N T D D F L Y Q D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 98.8 N.A. N.A. 92 92.4 N.A. N.A. 20.7 27.4 27.7 N.A. 56.8 57.4 47.2 51.4
Protein Similarity: 100 97 99.5 N.A. N.A. 96.3 96.7 N.A. N.A. 36 46.3 46 N.A. 75.5 74.6 65.7 67.9
P-Site Identity: 100 100 100 N.A. N.A. 100 100 N.A. N.A. 46.6 13.3 13.3 N.A. 60 66.6 66.6 6.6
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. N.A. 73.3 20 33.3 N.A. 80 93.3 80 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 54.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 8 0 70 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 8 77 8 70 0 0 0 8 % D
% Glu: 0 0 0 8 0 24 0 8 16 54 0 0 0 0 8 % E
% Phe: 16 8 31 0 0 0 0 0 0 0 8 8 0 0 0 % F
% Gly: 0 0 0 85 0 0 0 0 0 0 8 0 0 24 0 % G
% His: 0 0 0 0 0 0 16 0 0 8 0 8 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 0 24 0 0 % I
% Lys: 0 0 0 8 8 0 16 8 0 8 0 8 0 0 24 % K
% Leu: 77 8 0 0 0 0 8 0 0 8 8 8 47 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 8 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 16 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 8 0 0 0 8 0 8 8 % Q
% Arg: 0 0 0 0 0 77 39 8 0 0 0 0 8 0 39 % R
% Ser: 0 0 0 0 16 0 0 39 8 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % T
% Val: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 16 0 0 0 0 0 0 0 0 % W
% Tyr: 8 77 62 0 0 0 0 0 0 8 0 54 8 70 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _