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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABO All Species: 25.15
Human Site: Y149 Identified Species: 61.48
UniProt: P16442 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16442 NP_065202.2 354 40934 Y149 M V G H R V H Y Y V F T D Q P
Chimpanzee Pan troglodytes XP_001169164 300 34650 L117 I P L G P H R L L S S I P I Q
Rhesus Macaque Macaca mulatta XP_001118424 353 40809 Y148 M V G H R V H Y Y V F T D Q P
Dog Lupus familis XP_548386 395 43861 Y190 M V G H R V T Y Y V F T D R P
Cat Felis silvestris
Mouse Mus musculus P38649 332 38758 D133 V I Y Y V F T D R P A D V P Q
Rat Rattus norvegicus Q9ET32 348 40356 Y144 M V G H K V I Y Y V F T D R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506735 371 42721 Y166 M M G H K V N Y Y V Y T D R P
Chicken Gallus gallus Q5ZLK4 343 39633 Y140 M K G Y R V N Y Y I F T D N P
Frog Xenopus laevis NP_001088652 338 40082 V134 G H Q V N Y Y V F T D L V R N
Zebra Danio Brachydanio rerio XP_001344683 347 39994 Y142 F V G F G V H Y Y L F T D Q P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 42.9 93.7 57.7 N.A. 70.6 73.4 N.A. 62.5 44.3 57.3 44.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 57.6 95.1 67.8 N.A. 78.5 83 N.A. 75.7 61 70 62.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 86.6 N.A. 0 80 N.A. 66.6 66.6 0 73.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 100 93.3 N.A. 20 93.3 N.A. 100 86.6 20 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 0 10 10 70 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 0 0 10 0 10 0 0 10 0 60 0 0 0 0 % F
% Gly: 10 0 70 10 10 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 10 0 50 0 10 30 0 0 0 0 0 0 0 0 % H
% Ile: 10 10 0 0 0 0 10 0 0 10 0 10 0 10 0 % I
% Lys: 0 10 0 0 20 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 0 0 0 10 10 10 0 10 0 0 0 % L
% Met: 60 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 20 0 0 0 0 0 0 10 10 % N
% Pro: 0 10 0 0 10 0 0 0 0 10 0 0 10 10 70 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 30 20 % Q
% Arg: 0 0 0 0 40 0 10 0 10 0 0 0 0 40 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 20 0 0 10 0 70 0 0 0 % T
% Val: 10 50 0 10 10 70 0 10 0 50 0 0 20 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 20 0 10 10 70 70 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _