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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPEP1 All Species: 29.7
Human Site: S319 Identified Species: 72.59
UniProt: P16444 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16444 NP_001121613.1 411 45674 S319 P E G L E D V S K Y P D L I A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001091399 411 45788 S319 P E G L E D V S K Y P D L I A
Dog Lupus familis XP_536748 410 45689 S319 P L G L E D V S K Y P D L V A
Cat Felis silvestris
Mouse Mus musculus P31428 410 45664 S319 P V G L E D V S K Y P D L I A
Rat Rattus norvegicus P31430 410 45504 S319 P V G L E D V S K Y P D L I A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511283 510 56609 S417 P E G L E D V S K Y P N L I A
Chicken Gallus gallus XP_414081 403 45181 S307 P E G L E D V S K Y P S L I E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001070805 413 46950 S321 P V G L E D V S K Y P D L V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_733146 434 47880 G345 G I D H V G I G A G Y D G V N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797192 420 47209 K318 A D H M D H I K E V C G W E C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 94.8 77.6 N.A. 71.7 73.7 N.A. 54.9 48.9 N.A. 57.1 N.A. 44.7 N.A. N.A. 50.7
Protein Similarity: 100 N.A. 97 87.3 N.A. 82.9 84.1 N.A. 65.4 63.9 N.A. 71.6 N.A. 61 N.A. N.A. 64.7
P-Site Identity: 100 N.A. 100 86.6 N.A. 93.3 93.3 N.A. 93.3 86.6 N.A. 80 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 N.A. 100 93.3 N.A. 93.3 93.3 N.A. 100 86.6 N.A. 86.6 N.A. 20 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 60 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % C
% Asp: 0 10 10 0 10 80 0 0 0 0 0 70 0 0 0 % D
% Glu: 0 40 0 0 80 0 0 0 10 0 0 0 0 10 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 80 0 0 10 0 10 0 10 0 10 10 0 0 % G
% His: 0 0 10 10 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 20 0 0 0 0 0 0 60 0 % I
% Lys: 0 0 0 0 0 0 0 10 80 0 0 0 0 0 0 % K
% Leu: 0 10 0 80 0 0 0 0 0 0 0 0 80 0 0 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % N
% Pro: 80 0 0 0 0 0 0 0 0 0 80 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 80 0 0 0 10 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 30 0 0 10 0 80 0 0 10 0 0 0 30 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 80 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _