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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPEP1 All Species: 30.91
Human Site: Y321 Identified Species: 75.56
UniProt: P16444 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16444 NP_001121613.1 411 45674 Y321 G L E D V S K Y P D L I A E L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001091399 411 45788 Y321 G L E D V S K Y P D L I A E L
Dog Lupus familis XP_536748 410 45689 Y321 G L E D V S K Y P D L V A E L
Cat Felis silvestris
Mouse Mus musculus P31428 410 45664 Y321 G L E D V S K Y P D L I A E L
Rat Rattus norvegicus P31430 410 45504 Y321 G L E D V S K Y P D L I A E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511283 510 56609 Y419 G L E D V S K Y P N L I A E L
Chicken Gallus gallus XP_414081 403 45181 Y309 G L E D V S K Y P S L I E E L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001070805 413 46950 Y323 G L E D V S K Y P D L V V E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_733146 434 47880 G347 D H V G I G A G Y D G V N L V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797192 420 47209 V320 H M D H I K E V C G W E C V G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 94.8 77.6 N.A. 71.7 73.7 N.A. 54.9 48.9 N.A. 57.1 N.A. 44.7 N.A. N.A. 50.7
Protein Similarity: 100 N.A. 97 87.3 N.A. 82.9 84.1 N.A. 65.4 63.9 N.A. 71.6 N.A. 61 N.A. N.A. 64.7
P-Site Identity: 100 N.A. 100 93.3 N.A. 100 100 N.A. 93.3 86.6 N.A. 86.6 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 100 86.6 N.A. 93.3 N.A. 26.6 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 0 0 0 0 60 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % C
% Asp: 10 0 10 80 0 0 0 0 0 70 0 0 0 0 0 % D
% Glu: 0 0 80 0 0 0 10 0 0 0 0 10 10 80 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 80 0 0 10 0 10 0 10 0 10 10 0 0 0 10 % G
% His: 10 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 20 0 0 0 0 0 0 60 0 0 0 % I
% Lys: 0 0 0 0 0 10 80 0 0 0 0 0 0 0 0 % K
% Leu: 0 80 0 0 0 0 0 0 0 0 80 0 0 10 80 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 80 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 80 0 0 0 10 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 10 0 80 0 0 10 0 0 0 30 10 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 80 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _