KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB42
All Species:
17.27
Human Site:
S27
Identified Species:
47.5
UniProt:
P16452
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16452
NP_000110.2
691
77009
S27
E
H
H
T
K
A
L
S
S
R
R
L
F
V
R
Chimpanzee
Pan troglodytes
XP_001156126
691
77111
S27
E
H
H
T
K
A
L
S
S
R
R
L
F
V
R
Rhesus Macaque
Macaca mulatta
XP_001101645
766
85694
T73
R
H
H
T
E
E
I
T
V
D
H
L
L
V
R
Dog
Lupus familis
XP_851181
693
77465
S27
E
H
H
T
K
A
I
S
S
Q
H
L
I
V
R
Cat
Felis silvestris
Mouse
Mus musculus
P49222
691
76721
S27
E
H
Y
T
K
A
I
S
S
Q
H
L
T
L
R
Rat
Rattus norvegicus
P23606
824
90751
E143
E
H
H
T
D
E
F
E
Y
D
E
L
I
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q01841
689
77951
G27
E
H
R
T
E
E
M
G
S
Q
Q
L
V
V
R
Frog
Xenopus laevis
NP_001080912
690
77450
S27
S
H
R
T
A
E
A
S
C
E
Q
L
I
V
R
Zebra Danio
Brachydanio rerio
NP_997821
679
75754
G25
D
H
H
T
E
L
N
G
T
D
R
L
I
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
32.1
76.4
N.A.
72.9
23.9
N.A.
N.A.
35.1
35.3
34.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
48.2
85.4
N.A.
83.5
41.1
N.A.
N.A.
55.7
53.9
50.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
40
73.3
N.A.
60
40
N.A.
N.A.
46.6
40
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
60
86.6
N.A.
86.6
46.6
N.A.
N.A.
73.3
46.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
45
12
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
12
0
0
0
0
34
0
0
0
0
0
% D
% Glu:
67
0
0
0
34
45
0
12
0
12
12
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
0
23
0
0
% F
% Gly:
0
0
0
0
0
0
0
23
0
0
0
0
0
0
0
% G
% His:
0
100
67
0
0
0
0
0
0
0
34
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
34
0
0
0
0
0
45
0
0
% I
% Lys:
0
0
0
0
45
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
12
23
0
0
0
0
100
12
23
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
34
23
0
0
0
0
% Q
% Arg:
12
0
23
0
0
0
0
0
0
23
34
0
0
0
100
% R
% Ser:
12
0
0
0
0
0
0
56
56
0
0
0
0
0
0
% S
% Thr:
0
0
0
100
0
0
0
12
12
0
0
0
12
0
0
% T
% Val:
0
0
0
0
0
0
0
0
12
0
0
0
12
78
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
0
0
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _