KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MGMT
All Species:
26.06
Human Site:
S22
Identified Species:
63.7
UniProt:
P16455
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16455
NP_002403
207
21646
S22
P
L
G
K
L
E
L
S
G
C
E
Q
G
L
H
Chimpanzee
Pan troglodytes
XP_001142169
207
21582
S22
P
L
G
K
L
E
L
S
G
C
E
Q
G
L
H
Rhesus Macaque
Macaca mulatta
XP_001089785
207
21935
S22
P
L
G
K
L
E
L
S
G
C
E
Q
G
L
H
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P26187
211
22416
S22
P
L
G
K
M
E
L
S
G
C
E
R
G
L
H
Rat
Rattus norvegicus
P24528
209
22225
S22
P
L
G
K
I
E
L
S
G
C
E
R
G
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521529
115
12511
Chicken
Gallus gallus
XP_421823
258
28080
S96
P
V
G
K
L
E
I
S
G
C
E
T
G
V
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684479
187
20183
R24
P
V
G
E
I
L
L
R
G
C
E
K
G
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001191329
183
19555
T26
P
I
G
H
V
T
I
T
G
C
E
V
G
V
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P26188
188
21480
V20
E
V
T
G
A
F
L
V
F
R
E
K
T
Q
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
92.7
N.A.
N.A.
68.7
68.4
N.A.
36.2
42.2
N.A.
42
N.A.
N.A.
N.A.
N.A.
34.7
Protein Similarity:
100
98
94.1
N.A.
N.A.
77.2
77
N.A.
40.5
52.3
N.A.
55.5
N.A.
N.A.
N.A.
N.A.
50.2
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
86.6
N.A.
0
73.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
0
93.3
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
80
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
10
0
60
0
0
0
0
90
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
80
10
0
0
0
0
80
0
0
0
80
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
80
% H
% Ile:
0
10
0
0
20
0
20
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
60
0
0
0
0
0
0
0
20
0
0
0
% K
% Leu:
0
50
0
0
40
10
70
0
0
0
0
0
0
50
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
80
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
30
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
10
0
20
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
60
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
10
0
10
0
0
0
10
10
0
0
% T
% Val:
0
30
0
0
10
0
0
10
0
0
0
10
0
30
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _