KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MGMT
All Species:
16.97
Human Site:
T10
Identified Species:
41.48
UniProt:
P16455
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16455
NP_002403
207
21646
T10
K
D
C
E
M
K
R
T
T
L
D
S
P
L
G
Chimpanzee
Pan troglodytes
XP_001142169
207
21582
T10
K
A
C
E
M
K
H
T
T
L
D
S
P
L
G
Rhesus Macaque
Macaca mulatta
XP_001089785
207
21935
T10
K
A
C
E
M
K
R
T
V
L
D
S
P
L
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P26187
211
22416
S10
E
T
C
K
M
K
Y
S
V
L
D
S
P
L
G
Rat
Rattus norvegicus
P24528
209
22225
T10
E
I
C
K
M
K
Y
T
V
L
D
S
P
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521529
115
12511
Chicken
Gallus gallus
XP_421823
258
28080
A84
S
Q
C
Q
E
K
H
A
V
L
L
S
P
V
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684479
187
20183
V12
G
A
C
V
L
C
A
V
T
L
T
S
P
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001191329
183
19555
V14
A
A
C
D
L
A
T
V
V
L
A
T
P
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P26188
188
21480
T8
M
K
E
L
L
Y
Y
T
F
I
E
T
E
V
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
92.7
N.A.
N.A.
68.7
68.4
N.A.
36.2
42.2
N.A.
42
N.A.
N.A.
N.A.
N.A.
34.7
Protein Similarity:
100
98
94.1
N.A.
N.A.
77.2
77
N.A.
40.5
52.3
N.A.
55.5
N.A.
N.A.
N.A.
N.A.
50.2
P-Site Identity:
100
86.6
86.6
N.A.
N.A.
60
66.6
N.A.
0
40
N.A.
40
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
86.6
86.6
N.A.
N.A.
80
80
N.A.
0
53.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
40
0
0
0
10
10
10
0
0
10
0
0
0
0
% A
% Cys:
0
0
80
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
0
0
0
0
0
0
50
0
0
0
0
% D
% Glu:
20
0
10
30
10
0
0
0
0
0
10
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
80
% G
% His:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
10
0
0
0
10
0
% I
% Lys:
30
10
0
20
0
60
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
30
0
0
0
0
80
10
0
0
50
0
% L
% Met:
10
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
80
0
0
% P
% Gln:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
10
0
0
0
70
0
0
0
% S
% Thr:
0
10
0
0
0
0
10
50
30
0
10
20
0
0
10
% T
% Val:
0
0
0
10
0
0
0
20
50
0
0
0
0
30
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
30
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _