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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE6A
All Species:
4.55
Human Site:
S835
Identified Species:
7.69
UniProt:
P16499
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16499
NP_000431.2
860
99547
S835
Q
K
Q
Q
S
A
K
S
A
A
A
G
N
Q
P
Chimpanzee
Pan troglodytes
XP_518030
860
99527
S835
Q
K
Q
Q
S
A
K
S
A
A
A
G
N
Q
P
Rhesus Macaque
Macaca mulatta
XP_001107349
860
99509
P835
Q
K
Q
Q
S
A
K
P
A
A
A
G
N
Q
L
Dog
Lupus familis
XP_543934
846
97567
N822
V
K
K
Q
E
E
G
N
M
I
A
K
A
T
E
Cat
Felis silvestris
Mouse
Mus musculus
P27664
859
99628
Q835
Q
K
Q
Q
A
A
K
Q
A
A
S
G
N
Q
P
Rat
Rattus norvegicus
Q8VID6
935
104553
K911
K
W
E
E
L
H
Q
K
R
L
Q
V
S
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506083
861
99448
K835
Q
K
Q
E
T
S
K
K
A
A
A
G
N
P
A
Chicken
Gallus gallus
P52731
862
99990
A837
K
K
K
E
E
E
A
A
A
K
K
A
E
N
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007161
858
99513
E833
E
A
K
K
A
K
E
E
A
H
A
N
S
D
H
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
P875
H
D
H
G
A
S
V
P
A
S
P
C
S
A
A
Fruit Fly
Dros. melanogaster
Q9VFI9
1131
125621
N1062
K
L
S
K
T
L
Y
N
S
M
D
G
S
K
P
Honey Bee
Apis mellifera
XP_394107
1016
115998
L961
E
A
P
E
K
S
A
L
G
R
L
I
S
L
R
Nematode Worm
Caenorhab. elegans
P91119
710
81117
Q686
A
H
M
L
P
Q
M
Q
A
S
R
L
H
A
W
Sea Urchin
Strong. purpuratus
NP_001029121
949
108476
Q910
S
L
E
C
I
Q
K
Q
E
G
S
R
S
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
62.5
N.A.
94.6
25.4
N.A.
89.9
62.9
N.A.
77.2
25.1
24.3
23.2
23.3
33.1
Protein Similarity:
100
99.8
99.5
79.3
N.A.
96.7
45.3
N.A.
95.2
79.6
N.A.
87.3
44.5
40.9
42.1
43
53.3
P-Site Identity:
100
100
86.6
20
N.A.
80
0
N.A.
60
13.3
N.A.
13.3
6.6
13.3
0
6.6
6.6
P-Site Similarity:
100
100
86.6
33.3
N.A.
93.3
33.3
N.A.
80
40
N.A.
53.3
33.3
60
26.6
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
0
0
22
29
15
8
65
36
43
8
8
22
29
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
8
0
0
8
0
% D
% Glu:
15
0
15
29
15
15
8
8
8
0
0
0
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
8
0
8
8
0
43
0
0
8
% G
% His:
8
8
8
0
0
8
0
0
0
8
0
0
8
0
8
% H
% Ile:
0
0
0
0
8
0
0
0
0
8
0
8
0
0
0
% I
% Lys:
22
50
22
15
8
8
43
15
0
8
8
8
0
8
0
% K
% Leu:
0
15
0
8
8
8
0
8
0
8
8
8
0
8
8
% L
% Met:
0
0
8
0
0
0
8
0
8
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
15
0
0
0
8
36
8
0
% N
% Pro:
0
0
8
0
8
0
0
15
0
0
8
0
0
8
29
% P
% Gln:
36
0
36
36
0
15
8
22
0
0
8
0
0
29
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
8
8
8
0
0
8
% R
% Ser:
8
0
8
0
22
22
0
15
8
15
15
0
43
0
0
% S
% Thr:
0
0
0
0
15
0
0
0
0
0
0
0
0
15
0
% T
% Val:
8
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _