KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE6A
All Species:
38.79
Human Site:
S95
Identified Species:
65.64
UniProt:
P16499
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16499
NP_000431.2
860
99547
S95
L
L
Q
A
D
R
M
S
L
F
M
Y
R
T
R
Chimpanzee
Pan troglodytes
XP_518030
860
99527
S95
L
L
Q
A
D
R
M
S
L
F
M
Y
R
T
R
Rhesus Macaque
Macaca mulatta
XP_001107349
860
99509
S95
L
L
Q
A
D
R
M
S
L
F
M
Y
R
T
R
Dog
Lupus familis
XP_543934
846
97567
S97
N
G
T
P
E
V
A
S
R
L
L
D
I
T
P
Cat
Felis silvestris
Mouse
Mus musculus
P27664
859
99628
S95
L
L
R
A
D
R
V
S
L
F
M
Y
R
T
R
Rat
Rattus norvegicus
Q8VID6
935
104553
S162
R
A
L
L
R
K
A
S
S
L
P
P
T
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506083
861
99448
S95
L
L
H
A
D
R
M
S
L
F
M
Y
R
T
R
Chicken
Gallus gallus
P52731
862
99990
S97
L
L
A
R
D
R
C
S
M
F
I
C
R
S
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007161
858
99513
S96
M
I
R
A
D
R
M
S
L
F
M
Y
R
Q
R
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
S197
M
V
D
A
D
R
C
S
L
F
L
V
E
G
T
Fruit Fly
Dros. melanogaster
Q9VFI9
1131
125621
S282
L
T
H
A
D
R
G
S
L
F
L
A
K
G
T
Honey Bee
Apis mellifera
XP_394107
1016
115998
S221
L
T
H
A
D
R
G
S
L
F
L
A
K
G
P
Nematode Worm
Caenorhab. elegans
P91119
710
81117
S50
K
N
V
K
N
G
T
S
G
G
T
G
A
W
T
Sea Urchin
Strong. purpuratus
NP_001029121
949
108476
S153
L
T
N
G
D
R
C
S
L
F
L
A
R
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
62.5
N.A.
94.6
25.4
N.A.
89.9
62.9
N.A.
77.2
25.1
24.3
23.2
23.3
33.1
Protein Similarity:
100
99.8
99.5
79.3
N.A.
96.7
45.3
N.A.
95.2
79.6
N.A.
87.3
44.5
40.9
42.1
43
53.3
P-Site Identity:
100
100
100
13.3
N.A.
86.6
13.3
N.A.
93.3
53.3
N.A.
73.3
40
46.6
46.6
6.6
46.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
20
N.A.
93.3
73.3
N.A.
93.3
60
60
60
13.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
65
0
0
15
0
0
0
0
22
8
0
8
% A
% Cys:
0
0
0
0
0
0
22
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
8
0
79
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
79
0
0
0
0
0
% F
% Gly:
0
8
0
8
0
8
15
0
8
8
0
8
0
29
0
% G
% His:
0
0
22
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
8
0
8
0
0
% I
% Lys:
8
0
0
8
0
8
0
0
0
0
0
0
15
0
0
% K
% Leu:
65
43
8
8
0
0
0
0
72
15
36
0
0
0
0
% L
% Met:
15
0
0
0
0
0
36
0
8
0
43
0
0
0
0
% M
% Asn:
8
8
8
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
8
8
0
0
15
% P
% Gln:
0
0
22
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
8
0
15
8
8
79
0
0
8
0
0
0
58
0
50
% R
% Ser:
0
0
0
0
0
0
0
100
8
0
0
0
0
8
0
% S
% Thr:
0
22
8
0
0
0
8
0
0
0
8
0
8
50
29
% T
% Val:
0
8
8
0
0
8
8
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
43
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _