KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE6A
All Species:
39.7
Human Site:
T170
Identified Species:
67.18
UniProt:
P16499
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16499
NP_000431.2
860
99547
T170
C
D
F
V
D
I
L
T
E
Y
K
T
K
N
I
Chimpanzee
Pan troglodytes
XP_518030
860
99527
T170
C
D
F
V
D
I
L
T
E
Y
K
T
K
N
I
Rhesus Macaque
Macaca mulatta
XP_001107349
860
99509
T170
C
D
F
V
D
I
L
T
E
Y
K
T
K
N
I
Dog
Lupus familis
XP_543934
846
97567
T157
S
D
F
M
D
K
Q
T
G
Y
V
T
K
N
L
Cat
Felis silvestris
Mouse
Mus musculus
P27664
859
99628
T170
C
D
F
V
D
N
L
T
E
Y
Q
T
K
N
I
Rat
Rattus norvegicus
Q8VID6
935
104553
T219
I
S
N
D
L
D
L
T
S
L
S
Y
K
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506083
861
99448
T170
C
D
F
V
D
V
L
T
E
Y
E
T
K
N
I
Chicken
Gallus gallus
P52731
862
99990
T172
S
D
Y
L
D
K
K
T
G
Y
T
T
V
N
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007161
858
99513
T171
S
D
F
V
D
N
L
T
E
Y
E
T
K
N
V
Tiger Blowfish
Takifugu rubipres
Q1KKS3
903
102001
T270
S
D
E
I
D
K
L
T
G
Y
K
T
K
S
L
Fruit Fly
Dros. melanogaster
Q9VFI9
1131
125621
T358
N
C
E
I
D
L
K
T
G
Y
K
T
N
A
I
Honey Bee
Apis mellifera
XP_394107
1016
115998
T297
N
S
S
I
D
M
R
T
G
Y
K
T
T
L
I
Nematode Worm
Caenorhab. elegans
P91119
710
81117
E103
E
L
I
V
Q
N
D
E
G
A
F
S
C
R
K
Sea Urchin
Strong. purpuratus
NP_001029121
949
108476
T228
N
P
E
V
D
K
I
T
G
Y
K
T
H
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
62.5
N.A.
94.6
25.4
N.A.
89.9
62.9
N.A.
77.2
25.1
24.3
23.2
23.3
33.1
Protein Similarity:
100
99.8
99.5
79.3
N.A.
96.7
45.3
N.A.
95.2
79.6
N.A.
87.3
44.5
40.9
42.1
43
53.3
P-Site Identity:
100
100
100
53.3
N.A.
86.6
20
N.A.
86.6
40
N.A.
73.3
53.3
40
40
6.6
46.6
P-Site Similarity:
100
100
100
66.6
N.A.
93.3
26.6
N.A.
100
60
N.A.
86.6
73.3
53.3
53.3
13.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% A
% Cys:
36
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
65
0
8
86
8
8
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
22
0
0
0
0
8
43
0
15
0
0
0
0
% E
% Phe:
0
0
50
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
0
8
22
0
22
8
0
0
0
0
0
0
8
58
% I
% Lys:
0
0
0
0
0
29
15
0
0
0
50
0
65
0
8
% K
% Leu:
0
8
0
8
8
8
58
0
0
8
0
0
0
8
22
% L
% Met:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
8
% M
% Asn:
22
0
8
0
0
22
0
0
0
0
0
0
8
58
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
8
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% R
% Ser:
29
15
8
0
0
0
0
0
8
0
8
8
0
15
0
% S
% Thr:
0
0
0
0
0
0
0
93
0
0
8
86
8
0
0
% T
% Val:
0
0
0
58
0
8
0
0
0
0
8
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
86
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _