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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNB3
All Species:
52.73
Human Site:
S245
Identified Species:
77.33
UniProt:
P16520
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16520
NP_002066.1
340
37221
S245
G
E
A
I
C
T
G
S
D
D
A
S
C
R
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110414
296
32378
D203
A
I
C
T
G
S
D
D
A
S
C
R
L
F
D
Dog
Lupus familis
XP_855554
340
37138
S245
G
E
A
I
C
T
G
S
D
D
A
S
C
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61011
340
37222
S245
G
E
A
I
C
T
G
S
D
D
A
S
C
R
L
Rat
Rattus norvegicus
P52287
340
37162
S245
G
E
A
I
C
T
G
S
D
D
A
S
C
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508337
967
105634
S872
G
N
A
F
A
T
G
S
D
D
A
T
C
R
L
Chicken
Gallus gallus
XP_425517
337
36936
S242
G
E
A
I
C
T
G
S
D
D
A
T
C
R
L
Frog
Xenopus laevis
P79959
340
37311
S245
G
N
A
F
A
T
G
S
D
D
A
T
C
R
L
Zebra Danio
Brachydanio rerio
Q6PH57
340
37267
S245
G
N
A
F
A
T
G
S
D
D
A
T
C
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26308
340
37114
S245
G
Q
A
F
A
T
G
S
D
D
A
T
C
R
L
Honey Bee
Apis mellifera
XP_393976
341
37351
S246
G
Y
A
F
A
T
G
S
D
D
A
T
C
R
L
Nematode Worm
Caenorhab. elegans
P17343
340
37388
S245
G
N
A
F
A
T
G
S
D
D
A
T
C
R
L
Sea Urchin
Strong. purpuratus
XP_001176793
341
37543
S246
G
Y
A
F
A
T
G
S
D
D
A
T
C
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49178
380
41696
S268
G
H
R
F
G
T
G
S
D
D
G
T
C
R
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P49177
377
40987
S267
G
Y
R
F
G
T
G
S
D
D
G
T
C
R
L
Baker's Yeast
Sacchar. cerevisiae
P18851
423
46563
S289
G
M
S
I
V
A
G
S
D
N
G
A
I
N
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87
96.7
N.A.
97
96.4
N.A.
30.3
92.3
82.9
83.5
N.A.
77.3
79.7
81.4
79.4
Protein Similarity:
100
N.A.
87
98.5
N.A.
98.5
98.8
N.A.
33.2
97.6
92
92.6
N.A.
87.6
88.8
90
87.9
P-Site Identity:
100
N.A.
0
100
N.A.
100
100
N.A.
73.3
93.3
73.3
73.3
N.A.
73.3
73.3
73.3
73.3
P-Site Similarity:
100
N.A.
6.6
100
N.A.
100
100
N.A.
80
100
80
80
N.A.
86.6
80
80
80
Percent
Protein Identity:
N.A.
43.1
N.A.
44.3
32.6
N.A.
Protein Similarity:
N.A.
63.1
N.A.
63.1
51.7
N.A.
P-Site Identity:
N.A.
60
N.A.
60
33.3
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
66.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
75
0
44
7
0
0
7
0
75
7
0
0
0
% A
% Cys:
0
0
7
0
32
0
0
0
0
0
7
0
88
0
0
% C
% Asp:
0
0
0
0
0
0
7
7
94
88
0
0
0
0
7
% D
% Glu:
0
32
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
57
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
94
0
0
0
19
0
94
0
0
0
19
0
0
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
38
0
0
0
0
0
0
0
0
7
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
88
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
25
0
0
0
0
0
0
0
7
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
13
0
0
0
0
0
0
0
0
7
0
88
0
% R
% Ser:
0
0
7
0
0
7
0
94
0
7
0
25
0
0
0
% S
% Thr:
0
0
0
7
0
88
0
0
0
0
0
63
0
0
0
% T
% Val:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _