Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNB3 All Species: 60
Human Site: S74 Identified Species: 88
UniProt: P16520 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16520 NP_002066.1 340 37221 S74 S K L L V S A S Q D G K L I V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001110414 296 32378 G33 L V S A S Q D G K L I V W D S
Dog Lupus familis XP_855554 340 37138 S74 S K L L V S A S Q D G K L I V
Cat Felis silvestris
Mouse Mus musculus Q61011 340 37222 S74 S K L L V S A S Q D G K L I V
Rat Rattus norvegicus P52287 340 37162 S74 S K L L V S A S Q D G K L I V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508337 967 105634 S701 S R L L V S A S Q D G K L I I
Chicken Gallus gallus XP_425517 337 36936 S71 S K L L V S A S Q D G K L I V
Frog Xenopus laevis P79959 340 37311 S74 S R L L V S A S Q D G K L I I
Zebra Danio Brachydanio rerio Q6PH57 340 37267 S74 S R L L V S A S Q D G K L I I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26308 340 37114 S74 S R N L V S A S Q D G K L I V
Honey Bee Apis mellifera XP_393976 341 37351 S75 S R N L V S A S Q D G K L I V
Nematode Worm Caenorhab. elegans P17343 340 37388 S74 S R N L V S A S Q D G K L I V
Sea Urchin Strong. purpuratus XP_001176793 341 37543 S75 S R N L V S A S Q D G K L I V
Poplar Tree Populus trichocarpa
Maize Zea mays P49178 380 41696 S85 K N W I V S A S Q D G R L I V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P49177 377 40987 S84 R N R I V S A S Q D G R L I V
Baker's Yeast Sacchar. cerevisiae P18851 423 46563 S111 S K R I L S A S Q D G F M L I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 87 96.7 N.A. 97 96.4 N.A. 30.3 92.3 82.9 83.5 N.A. 77.3 79.7 81.4 79.4
Protein Similarity: 100 N.A. 87 98.5 N.A. 98.5 98.8 N.A. 33.2 97.6 92 92.6 N.A. 87.6 88.8 90 87.9
P-Site Identity: 100 N.A. 0 100 N.A. 100 100 N.A. 86.6 100 86.6 86.6 N.A. 86.6 86.6 86.6 86.6
P-Site Similarity: 100 N.A. 6.6 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 93.3 93.3 93.3 93.3
Percent
Protein Identity: N.A. 43.1 N.A. 44.3 32.6 N.A.
Protein Similarity: N.A. 63.1 N.A. 63.1 51.7 N.A.
P-Site Identity: N.A. 66.6 N.A. 66.6 53.3 N.A.
P-Site Similarity: N.A. 80 N.A. 80 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 0 94 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 7 0 0 94 0 0 0 7 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 7 0 0 94 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 19 0 0 0 0 0 0 7 0 0 88 25 % I
% Lys: 7 38 0 0 0 0 0 0 7 0 0 75 0 0 0 % K
% Leu: 7 0 50 75 7 0 0 0 0 7 0 0 88 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 13 25 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 7 0 0 94 0 0 0 0 0 0 % Q
% Arg: 7 44 13 0 0 0 0 0 0 0 0 13 0 0 0 % R
% Ser: 82 0 7 0 7 94 0 94 0 0 0 0 0 0 7 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 7 0 0 88 0 0 0 0 0 0 7 0 0 69 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 7 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _