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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNB3
All Species:
24.24
Human Site:
T217
Identified Species:
35.56
UniProt:
P16520
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16520
NP_002066.1
340
37221
T217
L
W
D
V
R
E
G
T
C
R
Q
T
F
T
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110414
296
32378
Q176
V
R
E
G
T
C
R
Q
T
F
T
G
H
E
S
Dog
Lupus familis
XP_855554
340
37138
T217
L
W
D
V
R
E
G
T
C
R
Q
T
F
T
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61011
340
37222
T217
L
W
D
V
R
E
G
T
C
R
Q
T
F
T
G
Rat
Rattus norvegicus
P52287
340
37162
T217
L
W
D
V
R
E
G
T
C
R
Q
T
F
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508337
967
105634
M844
L
W
D
V
R
E
G
M
C
R
Q
T
F
T
G
Chicken
Gallus gallus
XP_425517
337
36936
T214
L
W
D
V
R
E
G
T
C
R
Q
T
F
S
G
Frog
Xenopus laevis
P79959
340
37311
M217
L
W
D
V
R
E
G
M
C
R
Q
T
F
T
G
Zebra Danio
Brachydanio rerio
Q6PH57
340
37267
M217
L
W
D
V
R
E
G
M
C
R
Q
T
F
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26308
340
37114
V217
L
W
D
I
R
E
G
V
C
K
Q
T
F
P
G
Honey Bee
Apis mellifera
XP_393976
341
37351
T218
L
W
D
I
R
E
G
T
C
K
Q
T
F
P
G
Nematode Worm
Caenorhab. elegans
P17343
340
37388
M217
L
W
D
I
R
D
G
M
C
K
Q
T
F
P
G
Sea Urchin
Strong. purpuratus
XP_001176793
341
37543
M218
L
W
D
I
R
E
G
M
C
K
Q
T
F
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49178
380
41696
T228
F
V
S
G
S
C
D
T
T
V
R
L
W
D
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P49177
377
40987
S227
F
I
S
G
S
C
D
S
T
A
R
L
W
D
T
Baker's Yeast
Sacchar. cerevisiae
P18851
423
46563
I254
G
S
D
G
Y
T
Y
I
W
D
S
R
S
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87
96.7
N.A.
97
96.4
N.A.
30.3
92.3
82.9
83.5
N.A.
77.3
79.7
81.4
79.4
Protein Similarity:
100
N.A.
87
98.5
N.A.
98.5
98.8
N.A.
33.2
97.6
92
92.6
N.A.
87.6
88.8
90
87.9
P-Site Identity:
100
N.A.
0
100
N.A.
100
100
N.A.
93.3
93.3
93.3
93.3
N.A.
73.3
80
66.6
80
P-Site Similarity:
100
N.A.
13.3
100
N.A.
100
100
N.A.
93.3
100
93.3
93.3
N.A.
86.6
93.3
86.6
93.3
Percent
Protein Identity:
N.A.
43.1
N.A.
44.3
32.6
N.A.
Protein Similarity:
N.A.
63.1
N.A.
63.1
51.7
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
20
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
19
0
0
75
0
0
0
0
0
0
% C
% Asp:
0
0
82
0
0
7
13
0
0
7
0
0
0
13
0
% D
% Glu:
0
0
7
0
0
69
0
0
0
0
0
0
0
7
0
% E
% Phe:
13
0
0
0
0
0
0
0
0
7
0
0
75
0
0
% F
% Gly:
7
0
0
25
0
0
75
0
0
0
0
7
0
0
75
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
7
0
25
0
0
0
7
0
0
0
0
0
0
7
% I
% Lys:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% K
% Leu:
75
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% L
% Met:
0
0
0
0
0
0
0
32
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
25
0
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
75
0
0
0
0
% Q
% Arg:
0
7
0
0
75
0
7
0
0
50
13
7
0
0
0
% R
% Ser:
0
7
13
0
13
0
0
7
0
0
7
0
7
7
13
% S
% Thr:
0
0
0
0
7
7
0
44
19
0
7
75
0
50
7
% T
% Val:
7
7
0
50
0
0
0
7
0
7
0
0
0
0
0
% V
% Trp:
0
75
0
0
0
0
0
0
7
0
0
0
13
0
0
% W
% Tyr:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _