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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPPB
All Species:
4.55
Human Site:
T74
Identified Species:
10
UniProt:
P16860
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16860
NP_002512.1
134
14726
T74
L
Q
E
S
P
R
P
T
G
V
W
K
S
R
E
Chimpanzee
Pan troglodytes
XP_525186
134
14686
T74
L
Q
E
S
P
R
P
T
G
V
W
K
A
R
E
Rhesus Macaque
Macaca mulatta
XP_001115574
99
10846
L41
S
D
L
E
T
S
G
L
Q
E
Q
H
N
H
L
Dog
Lupus familis
XP_544566
298
32072
A135
L
H
R
S
H
S
P
A
E
A
P
E
A
G
E
Cat
Felis silvestris
Mouse
Mus musculus
P40753
121
13738
Q64
Q
R
Q
L
L
K
D
Q
G
L
T
K
E
H
P
Rat
Rattus norvegicus
P13205
121
13637
Q64
Q
R
Q
L
S
K
D
Q
G
P
T
K
E
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
P84715
121
13130
L64
K
G
D
R
P
R
L
L
R
E
L
R
L
D
T
Chicken
Gallus gallus
P18908
140
15695
D80
P
E
L
T
D
D
S
D
E
Q
K
A
E
P
K
Frog
Xenopus laevis
NP_001088998
137
15362
D77
A
A
R
L
P
V
I
D
Q
D
D
I
V
S
Q
Zebra Danio
Brachydanio rerio
NP_942095
106
11510
E49
S
W
D
R
D
R
E
E
A
A
A
P
G
E
D
Tiger Blowfish
Takifugu rubipres
Q805D5
130
13773
A71
G
P
P
R
S
F
G
A
S
P
G
A
L
R
G
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
66.4
24.8
N.A.
33.5
36.5
N.A.
29.8
30
30.6
25.3
27.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.5
68.6
31.2
N.A.
53.7
53.7
N.A.
39.5
46.4
50.3
43.2
38
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
0
26.6
N.A.
13.3
13.3
N.A.
13.3
0
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
40
N.A.
40
33.3
N.A.
26.6
20
13.3
20
6.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
0
19
10
19
10
19
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
19
0
19
10
19
19
0
10
10
0
0
10
10
% D
% Glu:
0
10
19
10
0
0
10
10
19
19
0
10
28
10
28
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
0
19
0
37
0
10
0
10
10
10
% G
% His:
0
10
0
0
10
0
0
0
0
0
0
10
0
19
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% I
% Lys:
10
0
0
0
0
19
0
0
0
0
10
37
0
0
10
% K
% Leu:
28
0
19
28
10
0
10
19
0
10
10
0
19
10
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
10
10
10
0
37
0
28
0
0
19
10
10
0
10
10
% P
% Gln:
19
19
19
0
0
0
0
19
19
10
10
0
0
0
10
% Q
% Arg:
0
19
19
28
0
37
0
0
10
0
0
10
0
28
0
% R
% Ser:
19
0
0
28
19
19
10
0
10
0
0
0
10
10
0
% S
% Thr:
0
0
0
10
10
0
0
19
0
0
19
0
0
0
10
% T
% Val:
0
0
0
0
0
10
0
0
0
19
0
0
10
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
19
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _