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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPE All Species: 33.33
Human Site: Y199 Identified Species: 81.48
UniProt: P16870 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16870 NP_001864.1 476 53151 Y199 P D L D R I V Y V N E K E G G
Chimpanzee Pan troglodytes A5A6K7 476 53027 Y199 P D L D R I V Y V N E K E G G
Rhesus Macaque Macaca mulatta XP_001097378 620 69212 Y344 P D L D R I V Y V N E K E G G
Dog Lupus familis XP_532715 382 43038 Q127 N L K K I V D Q N T K L A P E
Cat Felis silvestris
Mouse Mus musculus Q00493 476 53237 Y199 P D L D R I V Y V N E K E G G
Rat Rattus norvegicus P15087 476 53290 Y199 P D L D R I V Y V N E K E G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509346 549 61162 Y272 P D L D R I V Y V N E R Q G G
Chicken Gallus gallus Q8QGP3 647 73900 Y330 P D L T S E A Y R R A G I R G
Frog Xenopus laevis NP_001121285 464 52326 Y187 P D L D R I V Y L N E R E G G
Zebra Danio Brachydanio rerio NP_999975 454 51264 Y177 P D L D R I V Y M N E R E G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 76.2 77.3 N.A. 96.6 96.2 N.A. 71.5 36.1 79.1 77.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 76.4 78.7 N.A. 97.9 98.1 N.A. 76.6 49.7 88.4 89 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 100 100 N.A. 86.6 33.3 86.6 86.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 13.3 N.A. 100 100 N.A. 100 33.3 100 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 0 0 10 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 90 0 80 0 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 10 0 0 0 0 80 0 70 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 10 0 80 90 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 80 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 0 10 10 0 0 0 0 0 0 10 50 0 0 0 % K
% Leu: 0 10 90 0 0 0 0 0 10 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 10 80 0 0 0 0 0 % N
% Pro: 90 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 0 80 0 0 0 10 10 0 30 0 10 0 % R
% Ser: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % T
% Val: 0 0 0 0 0 10 80 0 60 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 90 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _