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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCG2
All Species:
24.24
Human Site:
T332
Identified Species:
48.48
UniProt:
P16885
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16885
NP_002652.2
1265
147870
T332
S
S
H
N
T
Y
L
T
G
D
Q
L
R
S
E
Chimpanzee
Pan troglodytes
XP_001147944
1265
147906
T332
S
S
H
N
T
Y
L
T
G
D
Q
L
R
S
E
Rhesus Macaque
Macaca mulatta
XP_001111677
1265
147898
T332
S
S
H
N
T
Y
L
T
G
D
Q
L
R
S
E
Dog
Lupus familis
XP_546812
1252
146274
T332
S
S
H
N
T
Y
L
T
G
D
Q
L
R
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIH5
1265
147573
T332
S
S
H
N
T
Y
L
T
G
D
Q
L
R
S
E
Rat
Rattus norvegicus
P24135
1265
147716
T332
S
S
H
N
T
Y
L
T
G
D
Q
L
R
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508105
991
115582
S133
V
Q
G
S
A
F
D
S
G
L
G
I
S
L
R
Chicken
Gallus gallus
Q2VRL0
637
72514
Frog
Xenopus laevis
Q32NH8
758
87399
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624101
1134
132613
A276
S
C
Q
A
Y
V
R
A
L
R
T
G
C
R
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784329
940
107748
Q82
F
G
D
T
L
L
T
Q
P
I
D
R
D
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98
94.4
N.A.
94.1
94.7
N.A.
62.7
20.7
22.1
21.2
N.A.
N.A.
40.9
N.A.
32.9
Protein Similarity:
100
99.9
99.2
97
N.A.
97.1
97.3
N.A.
67.8
33.2
37.5
34.9
N.A.
N.A.
59.1
N.A.
49
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
0
0
0
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
0
0
0
N.A.
N.A.
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
0
0
9
0
0
0
0
0
9
9
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
9
% C
% Asp:
0
0
9
0
0
0
9
0
0
50
9
0
9
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% E
% Phe:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
0
0
0
0
0
59
0
9
9
0
0
0
% G
% His:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
9
9
50
0
9
9
0
50
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
9
9
0
0
0
0
9
0
0
50
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
9
0
0
9
0
9
50
9
9
% R
% Ser:
59
50
0
9
0
0
0
9
0
0
0
0
9
50
0
% S
% Thr:
0
0
0
9
50
0
9
50
0
0
9
0
0
0
0
% T
% Val:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
50
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _