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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSDA All Species: 18.18
Human Site: Y177 Identified Species: 44.44
UniProt: P16989 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16989 NP_003642.3 372 40090 Y177 Y A A D R R R Y R R G Y Y G R
Chimpanzee Pan troglodytes XP_520744 588 63523 Y396 Y A A D R R R Y R R G Y Y G R
Rhesus Macaque Macaca mulatta XP_001118505 407 44209 Y212 Y A A D R R R Y R R G Y Y G R
Dog Lupus familis XP_549033 383 41614 R195 F T E A Q G Q R R R L P G G P
Cat Felis silvestris
Mouse Mus musculus Q9JKB3 361 38795 Y169 Y A A D R R R Y R R G Y Y G R
Rat Rattus norvegicus Q62764 361 38833 Y169 Y A A D R R R Y R R G Y Y G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q06066 321 35781 Q157 G P P R N Y Q Q N Y Q N S E S
Frog Xenopus laevis P21573 303 34615 N139 P P R N Y Q Q N Y Q N N E S G
Zebra Danio Brachydanio rerio NP_001119929 309 34906 D145 Y Q E N Y Q S D P E A E P R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRN5 195 21575 P31 N P A N L A S P T E E C G C V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.7 89.6 41.5 N.A. 86.5 87.6 N.A. N.A. 54 49.1 50.2 N.A. 22.5 N.A. N.A. N.A.
Protein Similarity: 100 62.7 90.6 54.3 N.A. 89.5 90.5 N.A. N.A. 62.3 56.7 58.5 N.A. 34.6 N.A. N.A. N.A.
P-Site Identity: 100 100 100 20 N.A. 100 100 N.A. N.A. 0 0 6.6 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 40 N.A. 100 100 N.A. N.A. 6.6 26.6 20 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 50 60 10 0 10 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % C
% Asp: 0 0 0 50 0 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 20 0 0 0 0 0 0 20 10 10 10 10 10 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 10 0 0 0 0 50 0 20 60 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 30 10 0 0 10 10 0 10 20 0 0 0 % N
% Pro: 10 30 10 0 0 0 0 10 10 0 0 10 10 0 10 % P
% Gln: 0 10 0 0 10 20 30 10 0 10 10 0 0 0 0 % Q
% Arg: 0 0 10 10 50 50 50 10 60 60 0 0 0 10 50 % R
% Ser: 0 0 0 0 0 0 20 0 0 0 0 0 10 10 10 % S
% Thr: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 60 0 0 0 20 10 0 50 10 10 0 50 50 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _