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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NAGA All Species: 37.58
Human Site: Y169 Identified Species: 75.15
UniProt: P17050 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17050 NP_000253.1 411 46565 Y169 P E E R A Q G Y P K M A A A L
Chimpanzee Pan troglodytes XP_525662 411 46627 Y169 P E E R A Q G Y P K M A A A L
Rhesus Macaque Macaca mulatta XP_001102266 636 70184 Y394 A E E R A Q G Y P K M A A A L
Dog Lupus familis XP_538347 411 46388 Y169 P E E R A K G Y P M M A A A L
Cat Felis silvestris
Mouse Mus musculus Q9QWR8 415 47216 Y169 S R E R A E G Y P K M A A A L
Rat Rattus norvegicus Q66H12 415 46853 Y169 P K E R A E G Y P K M A A A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90744 405 45597 Y153 G K E Q A Q G Y P Q M A R A L
Frog Xenopus laevis NP_001085328 400 44836 Y159 S T E K A L G Y P K M S E A L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609354 413 47029 Y169 P Y D M D H G Y S T F G R L L
Honey Bee Apis mellifera XP_001121693 462 52249 Y195 P S E M D R G Y P E F G F Y L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792642 415 46587 Y177 P K T M D K G Y P Q M T K Y L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P41946 471 52069 Y167 P D V S Y H R Y K A M S D A L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 60.6 84.4 N.A. 81.9 81.6 N.A. N.A. 70.8 56.2 N.A. N.A. 50.3 45.4 N.A. 51
Protein Similarity: 100 99.7 61.7 91.7 N.A. 89.4 89.1 N.A. N.A. 81 70.8 N.A. N.A. 64.8 61.9 N.A. 68.4
P-Site Identity: 100 100 93.3 86.6 N.A. 80 86.6 N.A. N.A. 66.6 60 N.A. N.A. 26.6 40 N.A. 40
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 100 N.A. N.A. 86.6 73.3 N.A. N.A. 33.3 53.3 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 67 0 0 0 0 9 0 59 50 75 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 9 0 25 0 0 0 0 0 0 0 9 0 0 % D
% Glu: 0 34 75 0 0 17 0 0 0 9 0 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 17 0 9 0 0 % F
% Gly: 9 0 0 0 0 0 92 0 0 0 0 17 0 0 0 % G
% His: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 25 0 9 0 17 0 0 9 50 0 0 9 0 0 % K
% Leu: 0 0 0 0 0 9 0 0 0 0 0 0 0 9 100 % L
% Met: 0 0 0 25 0 0 0 0 0 9 84 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 67 0 0 0 0 0 0 0 84 0 0 0 0 0 0 % P
% Gln: 0 0 0 9 0 34 0 0 0 17 0 0 0 0 0 % Q
% Arg: 0 9 0 50 0 9 9 0 0 0 0 0 17 0 0 % R
% Ser: 17 9 0 9 0 0 0 0 9 0 0 17 0 0 0 % S
% Thr: 0 9 9 0 0 0 0 0 0 9 0 9 0 0 0 % T
% Val: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 9 0 0 100 0 0 0 0 0 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _