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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NAGA All Species: 18.48
Human Site: Y351 Identified Species: 36.97
UniProt: P17050 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17050 NP_000253.1 411 46565 Y351 R T D M P Y R Y H S S L G Q L
Chimpanzee Pan troglodytes XP_525662 411 46627 Y351 R T D M P Y R Y H S S L G Q L
Rhesus Macaque Macaca mulatta XP_001102266 636 70184 Y576 R T D M P Y H Y H S S L G Q L
Dog Lupus familis XP_538347 411 46388 Y351 R T D I P Y H Y H S S L A Q L
Cat Felis silvestris
Mouse Mus musculus Q9QWR8 415 47216 F351 R T D M P F R F H C S L L E L
Rat Rattus norvegicus Q66H12 415 46853 F351 R T D M P Y H F H C S L L E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90744 405 45597 Y335 R T D M P F R Y T T S L A K L
Frog Xenopus laevis NP_001085328 400 44836 P340 G T D G L P R P Y T T S L G L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609354 413 47029 N336 P I G P L Y Q N F Y S Y A I A
Honey Bee Apis mellifera XP_001121693 462 52249 V382 T D G T P S D V S V T L K E L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792642 415 46587 L349 F T W P T V F L N R G A G G Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P41946 471 52069 S380 L E E I F F D S N L G S K E L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 60.6 84.4 N.A. 81.9 81.6 N.A. N.A. 70.8 56.2 N.A. N.A. 50.3 45.4 N.A. 51
Protein Similarity: 100 99.7 61.7 91.7 N.A. 89.4 89.1 N.A. N.A. 81 70.8 N.A. N.A. 64.8 61.9 N.A. 68.4
P-Site Identity: 100 100 93.3 80 N.A. 66.6 66.6 N.A. N.A. 66.6 26.6 N.A. N.A. 13.3 20 N.A. 13.3
P-Site Similarity: 100 100 93.3 86.6 N.A. 86.6 80 N.A. N.A. 86.6 46.6 N.A. N.A. 20 33.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 9 25 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % C
% Asp: 0 9 67 0 0 0 17 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 9 0 0 0 0 0 0 0 0 0 0 34 0 % E
% Phe: 9 0 0 0 9 25 9 17 9 0 0 0 0 0 0 % F
% Gly: 9 0 17 9 0 0 0 0 0 0 17 0 34 17 0 % G
% His: 0 0 0 0 0 0 25 0 50 0 0 0 0 0 0 % H
% Ile: 0 9 0 17 0 0 0 0 0 0 0 0 0 9 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 17 9 0 % K
% Leu: 9 0 0 0 17 0 0 9 0 9 0 67 25 0 84 % L
% Met: 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 17 0 0 0 0 0 0 % N
% Pro: 9 0 0 17 67 9 0 9 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 9 0 0 0 0 0 0 34 0 % Q
% Arg: 59 0 0 0 0 0 42 0 0 9 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 9 0 9 9 34 67 17 0 0 0 % S
% Thr: 9 75 0 9 9 0 0 0 9 17 17 0 0 0 0 % T
% Val: 0 0 0 0 0 9 0 9 0 9 0 0 0 0 0 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 50 0 42 9 9 0 9 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _