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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HMGA1 All Species: 17.58
Human Site: S64 Identified Species: 55.24
UniProt: P17096 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P17096 NP_002122.1 107 11676 S64 P R G R P K G S K N K G A A K
Chimpanzee Pan troglodytes XP_001154232 248 27121 S205 P R G R P K G S K N K G A A K
Rhesus Macaque Macaca mulatta XP_001104215 107 11704 S64 P W G Q P K G S K N K G A A K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P17095 107 11595 S64 P R G R P K G S K N K G A A K
Rat Rattus norvegicus Q8K585 107 11688 S64 P R G R P K G S K N K G T A K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_989700 96 10410 G60 K N K A S S K G R K S S V T P
Frog Xenopus laevis NP_001087840 105 11583 A69 S A Q K K E E A S G E K R P R
Zebra Danio Brachydanio rerio NP_998333 101 10947 A64 V S R G K K A A A A S A P A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 42.3 85.9 N.A. N.A. 97.1 96.2 N.A. N.A. 64.4 28 42.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 42.3 90.6 N.A. N.A. 97.1 96.2 N.A. N.A. 76.6 40.1 55.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 N.A. N.A. 100 93.3 N.A. N.A. 0 0 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 N.A. N.A. 100 93.3 N.A. N.A. 6.6 33.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 13 0 0 13 25 13 13 0 13 50 75 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 13 13 0 0 0 13 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 63 13 0 0 63 13 0 13 0 63 0 0 13 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 13 0 13 13 25 75 13 0 63 13 63 13 0 0 63 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 13 0 0 0 0 0 0 0 63 0 0 0 0 0 % N
% Pro: 63 0 0 0 63 0 0 0 0 0 0 0 13 13 13 % P
% Gln: 0 0 13 13 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 50 13 50 0 0 0 0 13 0 0 0 13 0 13 % R
% Ser: 13 13 0 0 13 13 0 63 13 0 25 13 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 13 13 0 % T
% Val: 13 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % V
% Trp: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _