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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GOT1
All Species:
25.15
Human Site:
S149
Identified Species:
42.56
UniProt:
P17174
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17174
NP_002070.1
413
46248
S149
E
N
H
N
A
V
F
S
A
A
G
F
K
D
I
Chimpanzee
Pan troglodytes
A5A6K8
413
46215
S149
E
N
H
N
A
V
F
S
A
A
G
F
K
D
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543963
413
46395
S149
E
N
H
N
G
V
F
S
A
A
G
F
K
D
I
Cat
Felis silvestris
Mouse
Mus musculus
P05201
413
46213
S149
E
N
H
N
A
V
F
S
A
A
G
F
K
D
I
Rat
Rattus norvegicus
P13221
413
46410
S149
E
N
H
N
G
V
F
S
A
A
G
F
K
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507985
380
42638
G126
F
L
S
R
W
Y
N
G
T
N
N
T
A
T
P
Chicken
Gallus gallus
P00504
412
45917
M148
E
N
H
N
S
V
F
M
D
A
G
F
K
D
I
Frog
Xenopus laevis
NP_001080543
411
46052
M147
E
N
H
N
A
V
F
M
D
A
G
F
K
D
I
Zebra Danio
Brachydanio rerio
NP_998222
410
45964
S146
E
N
H
N
A
V
F
S
N
A
G
F
E
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611086
416
46069
T146
I
F
C
D
A
G
F
T
T
V
K
S
Y
R
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22067
408
45475
T146
V
F
K
K
A
G
F
T
T
V
A
D
Y
T
F
Sea Urchin
Strong. purpuratus
XP_794016
614
68362
E351
I
A
Q
N
T
D
M
E
V
R
K
Y
R
Y
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P46644
449
48936
T191
I
F
T
L
A
G
L
T
V
K
T
Y
R
Y
Y
Baker's Yeast
Sacchar. cerevisiae
P23542
418
46039
K148
I
F
E
N
Q
G
L
K
T
A
T
Y
P
Y
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
92.4
N.A.
91
90.3
N.A.
76
80.1
79.9
76.5
N.A.
55.2
N.A.
54.2
39.9
Protein Similarity:
100
100
N.A.
96.6
N.A.
96.3
95.6
N.A.
84.5
89.5
89.5
88.1
N.A.
70.9
N.A.
68.2
50.6
P-Site Identity:
100
100
N.A.
93.3
N.A.
100
93.3
N.A.
0
80
86.6
86.6
N.A.
13.3
N.A.
13.3
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
93.3
N.A.
0
86.6
86.6
93.3
N.A.
26.6
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.8
46.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.4
62.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
58
0
0
0
36
65
8
0
8
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
8
0
0
15
0
0
8
0
58
0
% D
% Glu:
58
0
8
0
0
0
0
8
0
0
0
0
8
0
0
% E
% Phe:
8
29
0
0
0
0
72
0
0
0
0
58
0
0
8
% F
% Gly:
0
0
0
0
15
29
0
8
0
0
58
0
0
0
0
% G
% His:
0
0
58
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
29
0
0
0
0
0
0
0
0
0
0
0
0
0
58
% I
% Lys:
0
0
8
8
0
0
0
8
0
8
15
0
50
0
0
% K
% Leu:
0
8
0
8
0
0
15
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
8
15
0
0
0
0
0
0
0
% M
% Asn:
0
58
0
72
0
0
8
0
8
8
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% P
% Gln:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
8
0
0
15
8
0
% R
% Ser:
0
0
8
0
8
0
0
43
0
0
0
8
0
0
0
% S
% Thr:
0
0
8
0
8
0
0
22
29
0
15
8
0
15
0
% T
% Val:
8
0
0
0
0
58
0
0
15
15
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
22
15
22
22
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _